Dementia Risk Score Touts ‘Nearly 100%’ Predictive Accuracy
A novel clinical risk score predicted the chance of future dementia with high accuracy, but raised questions from dementia experts. Using data from nearly 450,000 people in the U.K. Biobank cohort, Xi-jian Dai, PhD, of The Second Affiliated Hospital of Nanchang University in China, and colleagues developed a practical tool to predict individual risk of […]
7 Boundaries Adult Children Should Consider Setting With Their Parents
Setting boundaries with your parents as an adult isn’t always easy. But it may be necessary for your own well-being and the health of the relationship. Know that boundaries are for you. They’re a way to respect yourself and honor your needs. They’re not about controlling other people — in this case, your parents. Advertisement […]
Primary Care Visits Prior to Cancer Diagnosis Tied to Lower Mortality
Regularly visiting a primary care physician (PCP) before cancer diagnosis was associated with better disease outcomes among a cohort of patients from the Veterans Affairs health system. Compared with no prior visits, annual PCP use among over 200,000 veterans with 12 different tumor types was linked with lower odds of being diagnosed with metastatic disease […]
Outdoor Lighting at Night Tied to Diabetes Prevalence
Nighttime artificial outdoor lighting was associated with impaired glucose control and increased diabetes risk, a cross-sectional study in China showed. In a nationally representative sample of 98,658 adults, the prevalence of diabetes was 28% higher among people exposed to the greatest levels of artificial outdoor light compared with those who had the least exposure (adjusted […]
Twelve-Month Data Back Pegloticase-Methotrexate Gout Combo
PHILADELPHIA — Previous findings that adding methotrexate to pegloticase (Krystexxa) in patients with gout was more effective than pegloticase alone have now been extended to a full year of treatment. At month 12 in the randomized, 152-patient MIRROR RCT trial, 60% of patients receiving the combination had serum urate levels below the target of 6 […]
Biologic Shows Promise in Ongoing Food Allergy Trial
LOUISVILLE, Ky. — Omalizumab (Xolair) may be an effective therapy for patients with multiple food allergies, according to an ongoing phase III trial. Most of the first 60 patients with multiple food allergies enrolled in stage one of the OUtMATCH clinical trial were able to tolerate serving-sized portions of those foods a year after receiving […]
Terry Bradshaw’s Merkel Cell Carcinoma
With football back in action this fall, watchers of “Fox NFL Sunday” noticed that commentator and Hall of Fame quarterback Terry Bradshaw looked different. He appeared to have gained weight and seemed unsteady on his feet. Fans flooded social media with concerns about Bradshaw. This past week, Bradshaw decided to address those concerns. In November […]
A New Congress Will Face Pressing Healthcare Issues, Regardless of Who Is in Control
WASHINGTON — With some midterm election races too close to call and at least one Senate race headed for a December runoff, it remained unclear on Wednesday which political party would take control of the House or the Senate in 2023. However, observers said that some predictions could still be made about Congress’s potential health […]
Anticoagulation Again Flops for Outpatient COVID-19
CHICAGO — For outpatient COVID-19, prophylactic anticoagulation with rivaroxaban (Xarelto) did not improve outcomes in elevated thrombotic risk patients, the PREVENT trial showed. Compared with placebo, giving the direct-acting oral anticoagulant (DOAC) for 35 days in non-hospitalized patients with symptomatic COVID-19 who had at least one risk factor for thrombosis didn’t reduce thromboembolic events or […]
Tenofovir, Vaccine Combo Eliminates Mom-to-Child HBV Transmission
Earlier maternal tenofovir disoproxil fumarate (TDF) combined with infant vaccination completely eliminated vertical transmission of chronic hepatitis B virus (HBV) from highly viremic mothers, even without the use of hepatitis B immunoglobulin (HBIg), a randomized trial conducted in China found. At 28 weeks postpartum, mother-to-child transmission was an identical 0% with early maternal TDF therapy […]