6 Alcohol Rules You Really Shouldn’t Break, According To Nutritionists
Klaus Vedfelt via Getty Images The guidelines from the Centers for Disease Control and Prevention say women should not have more than one alcoholic drink daily and men should not have more than two. Alcohol is known to be a health risk. Research shows that it’s linked to certain cancers, can damage your liver, is […]
Switching Twice With Infliximab Biosimilars Not Linked With IBD Flare Risk
LAS VEGAS — Biosimilar switching was not tied to flare in patients with inflammatory bowel disease (IBD), according to a retrospective cohort study. Patients who switched from infliximab (Remicade) to an infliximab biosimilar, and then switched again to a different biosimilar or back to infliximab, were no more or less likely to experience a disease […]
Cabozantinib Plus Atezolizumab Delays Progression in mCRPC
SAN FRANCISCO — In patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease progressed on a novel hormonal therapy, the combination of cabozantinib (Cabometyx) plus atezolizumab (Tecentriq) improved radiographic progression-free survival (rPFS) versus a switch to a second hormonal agent, a phase III trial showed. The so-called CONTACT-02 study included patients with extrapelvic nodal or […]
New research finds half-cardio, half-strength training reduces cardiovascular disease risks
Approximately one in three deaths in the U.S. is caused by cardiovascular disease, according to the U.S. Centers for Disease Control and Prevention. A robust body of evidence shows aerobic exercise can reduce risks, especially for people who are overweight or obese. But few studies have compared results with resistance exercise — also known as […]
Gabapentinoids in COPD Patients May Raise Risk for Severe Exacerbations
Gabapentinoid use in patients with chronic obstructive pulmonary disease (COPD) was associated with a higher risk for severe exacerbations, a population-based cohort study from Canada indicated. Among more than 27,000 COPD patients, those who started therapy with the anticonvulsant for either epilepsy, neuropathic pain, or some other form of chronic pain had a 39% greater […]
Erectile Dysfunction Drugs Plus Nitrates Still a Losing Combination, Study Shows
As expected, men taking nitrates for stable coronary artery disease (CAD) fared poorly if they added certain erectile dysfunction (ED) drugs to their medicine cabinet, a Swedish population-based study found. Compared with nitrate users not on phosphodiesterase-5 (PDE5) inhibitor treatment for ED, those who had both types of drugs in their medication history tended to […]
Clinical Challenges: Managing Pediatric Crohn’s Disease
Pediatric Crohn’s disease (CD) is on the rise, with an estimated 40,000 U.S. children affected by this potentially growth-stunting condition. This increase is not an artifact of better detection. “Rather, it appears that Western diets, antibiotic exposure early in life, and dietary emulsifiers may contribute to disease pathogenesis,” said Jeffrey Hyams, MD, of Connecticut Children’s […]
Goodbye, Appendix. Hello, Crohn’s Disease?
ORLANDO – People who undergo appendectomy may have an increased risk for the development of Crohn’s disease (CD), but not ulcerative colitis (UC), according to a systematic review and meta-analysis. The meta-analysis showed a pooled OR of 1.57 (95% CI 1.01-2.43, P<0.00001) for CD in those who had gotten surgery of the mucosa-and-gut lymphoid tissue […]
Red Meat Consumption Tied to Higher Chance of UC Flare
ORLANDO – For people with inflammatory bowel disease (IBD), that hamburger may come with more than just a side of fries — red meat consumption was linked with a higher risk for ulcerative colitis (UC) flare, researchers reported. According to an analysis of data from the IBD Partners research, patients with UC who were in […]
National Database Study Finds Higher Risk for Barrett’s Esophagus in IBD
ORLANDO – People with inflammatory bowel disease (IBD) faced higher odds of Barrett’s esophagus (BE) and BE without dysplasia, but not BE-linked malignancy, according to a cross-sectional study. Among patients diagnosed with ulcerative colitis (UC), the prevalence of BE was 0.077%, while the prevalence of BE in patients with Crohn’s disease (CD) came in at […]