Cancer Risk in NAFLD Higher With Early Disease Onset
The risk for cancer in patients with nonalcoholic fatty liver disease (NAFLD) was highest among those with early-onset disease and declined at later ages of diagnosis, a matched cohort study found. Examining more than 60,000 participants from a prospective Chinese dataset revealed that the increased risk of malignancy with NAFLD was highest among patients diagnosed […]
Study Confirms Better Survival for HPV-Positive Cervical Cancer
Cervical cancer associated with detectable human papillomavirus (HPV+) RNA or DNA had significantly better outcomes, including survival, a large meta-analysis of published studies showed. Patients who tested positive for HPV had a 62% improvement in disease-free survival (DFS), 44% improvement in cancer-specific survival (CSS), and 41% improvement in overall survival (OS), as compared with patients […]
Delaying Esophageal Cancer Surgery After Neoadjuvant CRT Fails in Trial
Prolonging the time to surgery following neoadjuvant chemoradiotherapy (CRT) for esophageal cancer failed to improve histological complete response rates and may even worsen overall survival (OS), according to results from the randomized NeoRes II study. Among the subset with adenocarcinoma, complete response rates were not significantly better with the prolonged surgical approach (10-12 weeks) compared […]
Study Links Being Breastfed to Cancer Risk in Adulthood
Additional evidence for a possible link between breastfeeding and colorectal cancer (CRC) was found in a large cohort study. In two prospective cohorts of 158,696 women followed for more than 20 years, being breastfed in infancy was associated with a 23% increased risk of CRC in adulthood (HR 1.23, 95% CI 1.10-1.38, P<0.001), Chen Yuan, […]
Global Incidence of Early-Onset Cancer Has Surged Since 1990
The global incidence of early-onset cancer has increased by 79% over the last three decades, researchers reported. In 2019, new cancer diagnoses in people under 50 totaled 3.26 million compared with 1.82 million in 1990, according to Xue Li, PhD, of Zhejiang University School of Medicine in China, and colleagues. Meanwhile, 1.06 million people under […]
Prostate Cancer Is Not Just an ‘Old Man’s Disease’
Gabe Canales’ experience with low-risk prostate cancer nearly matches mine — with a couple of caveats, including a 27-year difference in the ages at which we were both diagnosed. I was 62 years old with a rising prostate-specific antigen (PSA) level, close to the average age of diagnosis. Canales was just 35. Canales, author of […]
Cancer Patients More Likely to Die During COVID Pandemic
Cancer patients experienced significantly higher rates of COVID-19-related deaths compared with the general public, according to two retrospective studies from the U.S. and Canada. In a cross-sectional study published in JAMA Oncology, researchers found that the winter Omicron surge of 2021-2022 was particularly deadly, as the number of deaths among U.S. cancer patients increased by […]
Antioxidants stimulate blood flow in tumors
Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumours, a new study from Karolinska Institutet published in The Journal of Clinical Investigation shows. The discovery corroborates the idea that dietary supplements containing antioxidants can accelerate tumour growth and metastasis. “We’ve found that antioxidants activate a mechanism that causes […]
High-fat diets alter gut bacteria, boosting colorectal cancer risk in mice
The prevalence of colorectal cancer in people under the age of 50 has risen in recent decades. One suspected reason: the increasing rate of obesity and high-fat diets. Now, researchers at the Salk Institute and UC San Diego have discovered how high-fat diets can change gut bacteria and alter digestive molecules called bile acids that […]
I’m A Breast Cancer Survivor. I Was Slighted And Belittled Throughout My Treatment.
The author in the recovering room following her breast cancer surgery on March 28, 2023. Courtesy of Joy Jenkins I was scared as I approached the receptionist at my oncologists’ office. I had recently been diagnosed with breast cancer at age 56 after my annual mammogram. I didn’t know yet how bad things were. Was […]