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People with obesity due to genetic predisposition have lower risk of cardiovascular disease

The risk of developing cardiovascular disease is lower in people with obesity who have a genetic predisposition for high BMI than people with obesity influenced mainly by environmental factors such as lifestyle, researchers from Karolinska Institutet report in eClinicalMedicine. There has been a global increase in the incidence of overweight and obesity over the past […]

Dementia Risk May Rise as Air Quality Worsens

Exposure to particulate matter smaller than 2.5 microns in diameter (PM2.5) was associated with increased risk of dementia, a meta-analysis suggested. Across 14 studies that assessed PM2.5, the overall risk of dementia rose by 4% (HR 1.04, 95% CI 0.99-1.09) for every 2 μg/m3 increase in average annual PM2.5 concentration, according to Marc Weisskopf, PhD, […]

10 Myths About Mental Illness in Crime Fiction

I’m the rare girl who went to medical school with a love of watching whodunits and ended up — 10 gruelling years later — a forensic psychiatrist. Forensic psychiatry is the most thrilling job imaginable, but forensic psychiatrists in mysteries and crime TV have some very different roles than we do in real life. We […]

Novel Drug Authorized for Critically Ill COVID-19 Patients

The FDA has issued an emergency use authorization (EUA) for vilobelimab (Gohibic) to treat critically ill adults with COVID-19. In the EUA for the first-in-class monoclonal anti-human complement factor C5a antibody, the agency specified that the therapy be initiated within 48 hours of invasive mechanical ventilation or extracorporeal membrane oxygenation (ECMO). It is given at […]

Post-Immunotherapy Combo Promising in Advanced RCC

Combination treatment with a hypoxia-inducible factor (HIF) 2α inhibitor and tyrosine kinase inhibitor induced responses in nearly a third of advanced renal cell carcinoma (RCC) patients previously treated with immunotherapy, a single-arm phase II study found. In the study of 52 patients, 30.8% (95% CI 18.7-45.1) had a confirmed objective response following treatment with belzutifan […]

What Drives Alzheimer’s in Women?

Female sex, early age at menopause, and hormone therapy use each were associated with higher regional tau in cognitively normal people with elevated beta-amyloid, cross-sectional PET data showed. The highest levels of tau were seen in hormone therapy users who had a delay of more than 5 years between menopause onset and the start of […]

Opinion | Moderna’s Steep COVID Vaccine Price: Corporate Greed or Capitalism?

On May 11, the U.S. public health emergency (PHE) for COVID-19 will end. And with it, many Americans will no longer have access to free, government-sponsored COVID vaccines. Under the Public Health Service (PHS) Act, the U.S. government purchased and distributed COVID-19 vaccines for free to its populace, regardless of insurance or citizenship status. The […]

Prescriptions for Stimulants Jumped During the Pandemic

Prescriptions for stimulants have risen in recent years, with the sharpest increases seen during the pandemic, according to the CDC. In an analysis of claims from employer-sponsored insurance, the percentage of enrollees with one or more prescription stimulant fills rose from 3.6% in 2016 to 4.1% in 2021, Melissa Danielson, MSPH, of the CDC, and […]

Journal Shows Its Commitment to Exploring AI in Medicine

The New England Journal of Medicine is charging ahead with its coverage of the impact of artificial intelligence (AI) in medicine, publishing a special report, a review, and an editorial in this week’s issue, and announcing the creation of a journal dedicated to AI. The special report, written by researchers from Microsoft, outlined potential medical […]

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