Deion Sanders’ Cancer Diagnosis: Here’s What to Know
After encountering treatment options “that scared me to death,” NFL Hall of Famer Deion Sanders anticipates a full recovery from bladder cancer and returning to the sidelines as head coach of the University of Colorado Buffaloes. Like so many cancers, his was discovered during routine follow-up; in his case, for a previous bout of blood […]
Buprenorphine for OUD Tied to Better Outcomes for Mother and Baby
Buprenorphine treatment was linked with better outcomes for mother and infant, according to a study of pregnant individuals with opioid use disorder (OUD). Among 14,463 maternal-infant dyads, there was a statistically significant lower rate of adverse pregnancy outcomes among those who were treated with buprenorphine compared to those who did not receive treatment (25.4% vs […]
Raludotatug Deruxtecan Promising in Platinum-Resistant Advanced Ovarian Cancer
SAN DIEGO — Treatment with raludotatug deruxtecan (R-DXd) led to an “exciting” response rate among patients with heavily pretreated, platinum-resistant advanced ovarian cancer, according to an early-phase trial. In a subgroup analysis of the first-in-human phase I study, there was one complete response and 17 partial responses among 37 evaluable patients treated with R-DXd, an […]
FDA Approves First-Ever Drug for Serious Liver Condition
The FDA granted accelerated approval to resmetirom (Rezdiffra) as the first treatment for adults with noncirrhotic non-alcoholic steatohepatitis (NASH), also now referred to as metabolic dysfunction-associated steatohepatitis (MASH). A once-daily oral agent, resmetirom is a liver-directed thyroid hormone receptor (THR)-β selective agonist designed to target key underlying causes of NASH; the drug is specifically indicated […]
Breastfeeding While Taking MS Monoclonal Antibody Drugs Appears Safe
Exposure to multiple sclerosis (MS) monoclonal antibody treatment during breastfeeding appeared to have no negative effect on the early development or health of infants, registry data in Germany showed. Over the first 3 years of follow-up, no links emerged between exposure to monoclonal antibody drugs and annual hospitalization (rate ratio [RR] 1.23, P=0.473), annual systemic […]
Two Pembrolizumab Trials in Head and Neck Cancer Yield Divergent Results
Two first-line trials involving pembrolizumab (Keytruda)-based combinations for the treatment of recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) delivered mixed results. While first-line pembrolizumab plus lenvatinib (Lenvima) significantly improved progression-free survival (PFS) and overall response rate (ORR) compared with pembrolizumab alone in patients with recurrent or metastatic HNSCC with PD-L1 combined positive […]
This Reviewer-Beloved Toenail Brace Legitimately Changed My Life
Amazon The CurveCorrect ingrown toenail home treatment kit. HuffPost and its publishing partners may receive a share from purchases made via links on this page. Every item is independently selected by the HuffPost Shopping team. Prices and availability are subject to change. The experts consulted for this story do not necessarily endorse the products ahead […]
Benralizumab Matches Mepolizumab for Rare Vasculitis
WASHINGTON — Treatment with benralizumab (Fasenra) was noninferior to mepolizumab (Nucala) for relapsing or refractory eosinophilic granulomatosis with polyangiitis (EGPA), the randomized MANDARA trial showed. Among 140 patients receiving standard therapy, the adjusted percentage of patients with remission at weeks 36 and 48 was 59% in the benralizumab group and 56% in the mepolizumab group, […]
FDA Approves Antibiotic Combination for Complicated UTIs
The FDA approved the combination of cefepime and enmetazobactam (Exblifep) for the treatment of adult patients with complicated urinary tract infections, including pyelonephritis. The agency’s decision was based on data from the phase III ALLIUM trial in which the β-lactam/β-lactamase inhibitor combination demonstrated superiority over piperacillin/tazobactam. Clinical efficacy was shown for Pseudomonas aeruginosa and among […]
FDA OKs First Cellular Therapy for Melanoma
The FDA approved the cellular therapy lifileucel (Amtagvi) for the treatment of patients with previously treated unresectable or metastatic melanoma, the agency announced Friday. Lifileucel, a cellular therapy with tumor-infiltrating lymphocytes (TILs), was approved through the accelerated approval pathway, and is the first FDA-approved tumor-derived T-cell immunotherapy, the FDA noted. “Unresectable or metastatic melanoma is […]