Engineered nanomaterial captures off-target cancer drug to prevent tissue damage: Super-capacity, cellulose-based material may enable high-dose targeted treatments
Standard chemotherapies may efficiently kill cancer cells, but they also pose significant risks to healthy cells, resulting in secondary illness and a diminished quality of life for patients. To prevent the previously unavoidable damage, researchers, led by Penn State, have developed a new class of nanomaterials engineered to capture chemotherapy drugs before they interact with […]
Healthy diet in early pregnancy reduces risk of gestational diabetes
Obesity is a significant risk factor for developing gestational diabetes mellitus, and an increasing number of pregnant women are overweight or obese. Dietary habits have an impact on both obesity and the onset of gestational diabetes mellitus. The mother-child study conducted at the University of Turku and Turku University Hospital in Finland examined the connection […]
Targeting IL-23 Succeeds in Psoriatic Arthritis
The monoclonal antibody risankizumab (Skyrizi) showed significant efficacy for psoriatic arthritis (PsA) in two phase III randomized trials, a researcher reported. In the KEEPSAKE 1 and 2 trials, 1,407 patients with active PsA were randomly assigned to receive subcutaneous risankizumab, 150 mg, or placebo at baseline and then at weeks 4 and 16. On the […]
U.S. Nursing Home Deaths Rise as Delta Spreads
Latest Coronavirus News MONDAY, Oct. 4, 2021 (HealthDay News) – There has been a significant increase in COVID-related deaths in nursing homes as the highly contagious Delta spreads across the country, a new analysis shows. “While the vast majority of COVID-19 deaths happened outside of nursing homes in July and August, the high […]
Most cases of never-smokers’ lung cancer treatable with mutation-targeting drugs: Available, FDA-approved drugs may be effective in targeting about 80% of never-smokers’ lung tumors
Despite smoking’s well-known role in causing lung cancer, a significant number of patients who develop lung tumors have never smoked. While scientists are still working to understand what spurs cancer in so-called “never-smokers,” a study led by scientists at Washington University School of Medicine in St. Louis demonstrates new possibilities for treating these baffling tumors. […]
New Study Finds Yet Another Health Benefit Of The COVID Vaccine
Getting the coronavirus vaccine provides one obvious and significant health benefit: It protects you from getting seriously sick or dying if you come into contact with the virus. That, in itself, is amazing. But new research published on Wednesday points to another striking benefit of rolling up your sleeves that should not be dismissed: People […]
PSMA PET Plus MRI Better Detects Clinically Significant Prostate Cancers
MRI combined with prostate-specific membrane antigen (PSMA) PET improved the detection of clinically significant prostate cancer compared with MRI alone, and can potentially allow for a reduction in the number of biopsies needed for diagnosis, according to results from the PRIMARY trial. The combined approach demonstrated an increase in negative predictive value for detecting prostate […]
Oral Drug Active in Teens With Atopic Dermatitis
Teenagers with moderate or severe atopic dermatitis (AD) had significant improvement at 12 weeks with the investigational oral Janus kinase (JAK) inhibitor abrocitinib plus topical therapy, a placebo-controlled trial showed. Almost half of the patients had clear or almost clear skin by clinician assessment (IGA), and about 70% of patients treated with either of two […]
Bell’s Palsy After COVID Vaccines Still Very Rare
No significant increased risk of Bell’s palsy was seen after the Pfizer-BioNTech mRNA vaccine, but risk did increase for people who received the CoronaVac (Sinovac Biotech) shot, a vaccine that uses an inactivated virus, an analysis in Hong Kong showed. Compared with the background population, the age-standardized difference for Bell’s palsy incidence was 41.5 (95% […]
Mice treated with this cytokine lose weight by ‘sweating’ fat
Treating obese mice with the cytokine known as TSLP led to significant abdominal fat and weight loss compared to controls, according to new research published Thursday in Science from researchers in the Perelman School of Medicine at the University of Pennsylvania. Unexpectedly, the fat loss was notassociated with decreased food intake or faster metabolism. Instead, […]