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Gene mutation discovered that causes language impairment, ADHD and myasthenia

Two studies have revealed that certain disorders of the CAPRIN1 gene have significant consequences for people. First, the research team showed that insufficient production of the protein CAPRIN1 in the brain can lead to developmental differences, including autism spectrum disorders, attention deficit hyperactivity disorder (ADHD), and language disorders. Furthermore, the scientists identified a specific mutation […]

Why Has This Young Man Lost the Ability to Squat and Clench His Fists?

Why has this 31-year-old man gradually developed significant stiffness in his joints, which is now preventing him from clenching his fists or squatting? That’s what Yafang Zhou, MD, PhD, of Xiangya Hospital in Hunan, China, and colleagues wanted to figure out. As they reported in JAMA Neurology, the man’s experience began about 6 months previously, […]

Intravitreal Methotrexate Reduces Reoperation After Retinal Detachment Repair

NEW YORK CITY — Postoperative intravitreal methotrexate for retinal detachment led to a significant reduction in reoperation and improved visual acuity, a retrospective chart review showed. The absolute difference in reoperation rate was small, greater than 1% without methotrexate versus 0.4% with three to five postoperative injections of the antiproliferative agent, but the difference translated […]

Link Between Neovascular Eye Disease, CVD Tracked to Retinal Lesions

NEW YORK CITY — Subretinal drusenoid deposits (SDD) had a significant association with underlying cardiovascular disease (CVD), adding a missing link between age-related macular degeneration (AMD) and CVD, a prospective study showed. Among 47 patients with CVD and AMD, 40 (85%) had SDD with or without subretinal drusen. An analysis aided by artificial intelligence showed […]

A better diet helps beat depression in young men

Young men with a poor diet saw a significant improvement in their symptoms of depression when they switched to a healthy Mediterranean diet, a new study shows. Depression is a common mental health condition that affects approximately 1 million Australians each year. It is a significant risk factor for suicide, the leading cause of death […]

Another Link Between Prostate Cancer Hormone Tx and Impaired Cognition

Hormonal therapy for advanced prostate cancer, particularly enzalutamide (Xtandi), had a significant association with cognitive impairment, an analysis of a large drug-safety database showed. Traditional hormonal therapy increased the odds of cognitive impairment by 47% versus men who did not receive the therapy. The odds more than doubled among men who received novel androgen receptor […]

Dramatic, Durable Hair Growth With Oral JAK Inhibitor

BOSTON — An oral Janus kinase (JAK) inhibitor produced significant, durable hair growth, including scalp, eyebrows, and eyelashes in patients with severe alopecia areata, according to long-term data from two randomized trials. Almost 40% of patients achieved a Severity of Alopecia Tool (SALT) score ≤20 (total percentage of hair loss) at 52 weeks with a […]

Dog feces and urine could be harming nature reserves, according to new study

New research finds that dogs being walked in nature reserves contribute a significant amount of nutrients to the environment through their faeces and urine, which researchers warn could negatively impact local biodiversity. The research is published in the British Ecological Society journal, Ecological Solutions and Evidence. Significant levels of fertilisation Researchers at Ghent University have […]

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