Yellow Fever Vaccine Potency Wanes Over Time
SEATTLE — A single-dose of vaccine for yellow fever (YF-VAX strain 17D-204) is touted as offering lifelong protection, but the jab’s potency was reduced over time, researchers reported. In blood samples from 22 flavivirus-naïve individuals that were vaccinated for yellow fever within the last 10 years, 9% were 17D seronegative, and almost all (n=21/22) were […]
Monoclonal Antibody Shows Protection Against Malaria
SEATTLE — A monoclonal antibody delivered intravenously was effective in protecting against Plasmodium falciparum infection over a 6-month malaria season in Mali, a phase II placebo-controlled trial showed. Among 330 healthy adults, P. falciparum infection was detected in 35.5% who received a single dose of CIS43LS 10 mg/kg, 18.2% who received a 40-mg/kg dose, and […]