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If You Invite 455 People to Colonoscopy, You’ll Stop One Case of Cancer

Individuals invited to undergo screening colonoscopy had a lower risk of colorectal cancer compared with those who did not undergo screening, a European randomized trial found, though the reduction was lower than researchers had expected. In the Northern-European Initiative on Colorectal Cancer (NordICC) trial, an intention-to-screen analysis demonstrated that the risk of colorectal cancer at […]

Screening Colonoscopy with Add-On AI Could Save $290 million a Year

Using artificial intelligence (AI) during screening colonoscopy could be a cost-savings strategy that also could boost the prevention of colorectal cancer (CRC) incidence and mortality, a researcher reported. Among a simulated cohort of patients at average risk for CRC, and compared with no screening, the relative reduction of CRC incidence was 44.2% with screening colonoscopy […]

Just How Effective Is PSA Screening?

NEW ORLEANS — Prostate cancer screening with prostate-specific antigen (PSA) blood testing appears to have a more favorable benefit-to-harm trade-off than originally estimated, particularly among Black men, according to research presented here. Using the most conservative assumptions about the benefits of screening, investigators found that among men of all races, one death was prevented for […]

Are the Right Men Getting Screened for Prostate Cancer?

Prostate-specific antigen (PSA)-based screening for prostate cancer increased after the U.S. Preventive Services Task Force recommended individual decision-making for men ages 55 to 69 in 2017, reversing its 2012 guidance that advised against PSA screening in all men. Now, a retrospective cohort study found that from 2016 to 2019 the overall mean rate of PSA […]

What’s Behind the Racial Differences in Women’s Cancer Screening?

When it comes to racial disparities in cancer screening for women, factors such as disability, medical comorbidities, and insurance status may be playing an outsized role, a cross-sectional survey based in Chicago found. While women who identified as Black, Hispanic, or another race or ethnicity were significantly less likely than white women to be up […]

Novel Blood-Based Test Could Bolster MRI-Based Prostate Cancer Screening

Addition of a novel blood test to MRI-targeted biopsy in prostate cancer screening decreased overdetection while maintaining the ability to detect clinically significant cancer, Swedish researchers reported. They found that use of the test — called Stockholm3 — in a screening setting where MRI and targeted biopsies were used, performed at least as well as […]

Support for MRI-Targeted Biopsy in Prostate Cancer Screening

A prostate cancer screening strategy using MRI with targeted and standard biopsy reduced the detection of clinically insignificant cancers as well as unnecessary biopsies, researchers reported. Such an approach was also as effective as a standard biopsy strategy in detecting clinically significant cancers, said Tobias Nordstrom, MD, PhD, of the Karolinska Institutet in Stockholm, in […]

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