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Statin Reduced Risk of Heart Disease in People With HIV

BRISBANE, Australia — The cholesterol-lowering agent pitavastatin (Livalo) as primary prevention reduced the risk of major adverse cardiovascular events (MACE) among people living with HIV, the randomized REPRIEVE trial showed. Over a median follow-up of about 5 years, incidence of any MACE was 35% lower in the pitavastatin group compared with a placebo group, at […]

Near-Zero Risk of HIV Transmission With Low Viral Loads

BRISBANE, Australia – The risk of sexual transmission of HIV with viral loads of less than 1,000 copies per mL was almost zero, according to a meta-analysis and systematic review. In eight studies involving 7,762 serodiscordant couples across 25 countries, there were two cases of possible transmission among patients who had detectable viral loads that […]

Do certain amino acids modify the risk of dementia linked to air pollution?

Higher levels of vitamin B-related amino acids may be linked to the risk of dementia associated with a certain type of air pollutants called particulate matter, according to a study published in the July 19, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that […]

How dietary restraint could significantly reduce effects of genetic risk of obesity: Obesity risk genes make people feel hungrier and lose control over their eating, but practicing dietary restraint could counteract this.

Obesity risk genes make people feel hungrier and lose control over their eating, but practicing dietary restraint could counteract this. New research by University of Exeter, Exeter Clinical Research Facility, and University of Bristol — funded by the Medical Research Council Doctoral Training Partnership and published in the International Journal of Epidemiology — found that […]

Cardiorespiratory Fitness Levels May Influence Cancer Risk in Men

Cardiorespiratory fitness (CRF) levels may play a role in reducing the risk of developing and dying from certain common cancers in men, a prospective cohort study from Sweden suggested. Over a mean follow-up of 9.6 years among over 170,000 men, higher levels of CRF were associated with a significantly lower risk of incidence of colon […]

Agent Orange Exposure Tied to Bladder Cancer Risk in Veterans

Exposure to Agent Orange was associated with a modestly increased risk of bladder cancer among Vietnam War veterans, according to a retrospective cohort study. Among over 2.5 million male veterans, exposure to Agent Orange was associated with a relative 4% higher risk of bladder cancer (HR 1.04, 95% CI 1.02-1.06, P<0.001), reported Stephen Williams, MD, […]

Across Borders, Worse COVID Outcomes Seen in Polluted Areas

During the pandemic, people exposed to more air pollution were at greater risk of COVID-19 infection, hospitalization, and death, a nationwide study from Denmark showed. Based on the country’s COVID-19 surveillance system covering over 3.7 million residents, there were significant associations between local levels of inhalable particulate matter (PM2.5) and nitrogen dioxide (NO2) and incident […]

Americans With Heart Disease Less Likely to Use Wearable Devices

Fewer Americans with or at risk for cardiovascular disease (CVD) used a wearable health monitoring device than the general population, according to a nationally representative sample using 2019-2020 Health Information National Trends Survey (HINTS) data. Only 18% of adults with CVD and 26% of those at risk for CVD reported using a wearable device to […]

Insomnia Symptoms Tied to Stroke a Decade Later

Insomnia symptoms were associated with an increased risk for stroke, according to a population-cohort study using data from the Health and Retirement Study (HRS). People reporting less severe insomnia (HR 1.16, 95% CI 1.02-1.33) and more severe insomnia (HR 1.51, 95% CI 1.29-1.77) saw an increased risk of stroke over an average 9 years of […]

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