Mortality Risk From Damaged Bronchi Extends to People Without COPD
Bronchiectasis was associated with an increased mortality risk in current and former smokers even if they did not meet the spirometric criteria for chronic obstructive pulmonary disease (COPD), an observational study found. Compared with patients without suspected bronchiectasis, the 10-year mortality risk was greater among patients who had suspected bronchiectasis — evidenced by CT and […]
Cancer Risk in NAFLD Higher With Early Disease Onset
The risk for cancer in patients with nonalcoholic fatty liver disease (NAFLD) was highest among those with early-onset disease and declined at later ages of diagnosis, a matched cohort study found. Examining more than 60,000 participants from a prospective Chinese dataset revealed that the increased risk of malignancy with NAFLD was highest among patients diagnosed […]
One PrEP Regimen Linked to Higher Risk of Hypertension, Statin Use Over Another
Use of tenofovir alafenamide fumarate (TAF) for HIV pre-exposure prophylaxis (PrEP) was associated with an increased risk of hypertension and the initiation of statin use within 2 years compared with the use of tenofovir disoproxil fumarate (TDF; Viread), especially for people over age 40, a retrospective cohort study found. In a cohort of patients without […]
Prescription for fruits, vegetables linked to better heart health, food security
People at increased risk for cardiovascular disease who participated in produce prescription programs increased their consumption of fruits and vegetables, which was associated with improved body mass index (BMI), blood sugar and blood pressure levels, as well as a decrease in food insecurity. This new research was published today in Circulation: Cardiovascular Quality and Outcomes, […]
Dementia Risk From Midlife Onward Predicted With New Tool
A novel 14-year risk score helped identify people from age 50 onward at risk for all-cause dementia, a large U.K. study showed. The tool, called the U.K. Biobank Dementia Risk Score (UKBDRS), was developed and validated in two U.K. cohorts, reported Raihaan Patel, PhD, of the University of Oxford in England, and co-authors. The area […]
Pediatric Asthma Risk Score Robust Across Diverse Backgrounds
The Pediatric Asthma Risk Score (PARS) remained an effective tool for estimating asthma risk when used for patients of varying backgrounds, a study of 10 cohorts found. The area under the receiver operating curve (AUC) for the PARS assessment was 0.76 (95% CI 0.74-0.78), with AUC scores ranging from 0.61-0.83 across the cohorts, reported Gurjit […]
Some Health Workers See Double the Risk for Fatal Drug Overdoses
Certain healthcare workers including registered nurses (RNs) were at increased risk for fatal drug overdoses, a longitudinal study from 2008 to 2019 found. After adjustment for various factors, the risk for overdose death was more than twofold higher for RNs (HR 2.22, 95% CI 1.57-3.13) and social or behavioral health workers (HR 2.55, 95% CI […]
Breast Cancer Overdiagnosis Risk May Be Substantial for Older Women
Older women screened for breast cancer were at a considerable risk of being overdiagnosed, according to a large retrospective cohort study. Researchers found that an estimated 31% of breast cancers among screened women from the ages of 70 and 74 were potentially overdiagnosed, reported Ilana Richman, MD, MHS, of the Yale School of Medicine in […]
Albuminuria Testing Falling Short in Patients at Risk for CKD
Many cases of albuminuria may be missed in the U.S. due to lack of testing among patients at risk for chronic kidney disease (CKD), a cohort study suggested. Examining electronic health records for nearly 200,000 patients with hypertension or diabetes, only 17.5% underwent albuminuria testing, reported Chi D. Chu, MD, MAS, of the University of […]
Uncontrolled HIV a Risk Factor for Severe Mpox, Global Analysis Confirms
BRISBANE, Australia — The elevated risk of severe mpox in people living with HIV appeared restricted to those with uncontrolled HIV or immunosuppression from other conditions, according to an update on the global outbreak from World Health Organization (WHO) researchers. Of more than 32,000 cases of mpox (formerly monkeypox) reported worldwide where patients’ HIV status […]