Incomplete Polyp Resection Proves Tricky Business for Cancer Risk
Patients with incomplete colorectal polyp resections were at higher risk for more metachronous neoplasia and advanced neoplasia compared to patients who had a complete polyp resection, a post-hoc analysis suggested. More neoplastic polyps were found in patients with incomplete resections compared to complete resections (mean 0.8 vs 0.3, P=0.008), and these incomplete segments were at […]
Study identifies DNA signatures linked to heart disease
A new study identifies DNA signatures associated with risk for cardiovascular disease, a discovery that could lead to opportunities for clinical intervention years before symptoms manifest. Based on analyses of data from five large heart cohort studies of diverse populations, the findings are published in the journal JAMA Cardiology. “The science is rapidly advancing in […]
The Pill Can Spell Trouble for Long QTc
Some oral contraceptives were associated with greater cardiovascular risk among women with inherited long QT syndrome (LQTS), a registry study showed. Progestin-only oral contraceptive users had a 2.54-fold higher risk (95% CI 1.09-1.51) of a cardiac event compared with LQTS women not on oral contraceptives in multivariate analysis. Beta-blocker use appeared to mitigate that risk, […]
Shingrix OK’d For Immunocompromised Adults
FDA expanded the approval of Shingrix, an adjuvanted recombinant zoster vaccine, for adults at increased risk of shingles due to immunosuppression, manufacturer GlaxoSmithKline (GSK) announced on Monday. The expanded indication is for adults ages 18 and older at a greater risk of shingles due to “immunodeficiency or immunosuppression caused by known disease or therapy.” The […]
Vaginal Ring as Safe as Oral PrEP in Late Pregnancy
The long-acting dapivirine vaginal ring, which reduces HIV risk in young women, had a comparable safety profile in late pregnancy to an oral daily pre-exposure prophylaxis (PrEP) regimen, according to an interim analysis of a small open-label trial in sub-Saharan Africa. Adverse pregnancy outcomes were rare, with one stillbirth and one neonatal death in the […]
HIV Independently Tied to More Severe COVID-19
HIV was independently associated with a higher risk for severe or critical COVID-19, according to a World Health Organization (WHO) analysis. In a study of people living with HIV in Asia, Europe, Africa, and South America who also were hospitalized for COVID-19, HIV infection was linked with an increased risk of severe or critical COVID-19 […]
Ultra-processed food linked to higher risk of IBD: Further studies needed to identify contributory factors in processed foods that might account for these associations
A higher intake of ultra-processed food is associated with higher risk of inflammatory bowel disease (IBD), finds a study published by The BMJ today. Ultra-processed foods include packaged baked goods and snacks, fizzy drinks, sugary cereals, ready meals containing food additives, and reconstituted meat and fish products — often containing high levels of added sugar, […]
Which Came First: Low Testosterone Levels or Severe COVID-19?
Low testosterone levels in men with symptomatic COVID-19 were associated with a greater risk of severe illness or death, according to Italian researchers. Their case-control study found that, among men admitted to the emergency department of a Milan Hospital during the first wave of the pandemic, the lower the level of testosterone the higher the […]
Adult ADHD is linked to numerous physical conditions, study finds
Adults with ADHD are at higher risk of a wide range of physical conditions, including nervous system, respiratory, musculoskeletal, and metabolic diseases, according to a large register-based study from Karolinska Institutet in Sweden published in The Lancet Psychiatry. “Identifying co-occurring physical diseases may have important implications for treating adults with ADHD and for benefiting the […]
How To Stay Safe And Cool During A Heat Wave
It’s getting hot out there, and it’s not just the mercury that’s rising. The risk of heat-related illnesses has increased along with sizzling new temperature records that make it harder for the human body to naturally cool down to prevent injury or death, health officials warn. Heat waves have become more frequent around the contiguous […]