The future of flooding in Venice: improving projections, predictions and protection in the face of expected sea level rise
A new assessment of flood risk in Venice indicates that the impact of higher emissions on relative sea level rise during this century will be critical in planning future defence infrastructure for Venice and other coastal cities, state the authors of a new special issue published in Natural Hazards and Earth System Sciences today. The […]
Antibiotics linked to increased risk of colon cancer
There is a clear link between taking antibiotics and an increased risk of developing colon cancer within the next five to ten years. This has been confirmed by researchers at Umeå University, Sweden, after a study of 40,000 cancer cases. The impact of antibiotics on the intestinal microbiome is thought to lie behind the increased […]
CDC Staff Floats ‘Risk-Based Approach’ to Potential Booster Doses
A risk-based booster dose strategy for COVID-19 vaccines could target populations at risk of severe disease and those critical to the public health infrastructure, CDC staff said at a meeting of CDC’s Advisory Committee on Immunization Practices (ACIP) on Monday. Though FDA has yet to review data on booster doses for COVID-19 vaccines among the […]
Finerenone improves outcomes in patients with mild-to-moderate kidney disease and diabetes
Finerenone reduces the risk of cardiovascular morbidity and mortality in patients with mild-to-moderate kidney disease and type 2 diabetes. That’s the finding of late breaking research presented in a Hot Line session today at ESC Congress 20211 and published in the New England Journal of Medicine2. Diabetic kidney disease develops in approximately 40% of patients […]
Certain Groups Left Behind in HIV Preventive Care
Black and Hispanic individuals at risk for HIV, as well as young adults and people with substance use disorder (SUD), were more likely to experience gaps in preexposure prophylaxis (PrEP) care, a retrospective study showed. Examining electronic health record (EHR) data of people linked to PrEP care from 2012 to 2019, Black (HR 0.74, 95% […]
Mom’s Obesity During Pregnancy Linked to Colon Cancer in Offspring
Overweight and obesity in mothers during pregnancy increased the risk for colorectal cancer (CRC) in their children later on in life, according to a population-based study. Compared with underweight/healthy weight during pregnancy, both obesity and overweight were associated with increased risk of CRC in offspring (adjusted HR 2.51, 95% CI 1.05-6.02 and adjusted HR 2.12, […]
Brain-Eating Amoeba: Symptoms, Causes, Treatment & Survival
What are risk factors for Naegleria fowleri infection? The source of nearly all of the Naegleria fowleri infections reported since 1962 in the U.S. has been exposure to untreated freshwater during the summer. Activities that pose a risk include submerging the head, jumping feet first, diving, and sports that pull a person behind a boat, […]
Rheumatic Events With Checkpoint Inhibitors: Tumor Type Matters
Among the factors that were associated with an increased risk for the development of rheumatic immune-related adverse events following cancer treatment with immune checkpoint inhibitors (ICIs) was the type of malignancy involved, a large case-control study found. Compared with reference lung cancer (the most common type of malignancy in this cohort), the development of a […]
Study Confirms, Clarifies Excess Mortality in Testicular Cancer Survivors
Platinum-based chemotherapy (PBCT) and radiation therapy (RT) for testicular cancer significantly increased the risk of premature death from other causes, especially secondary cancers, a large Norwegian study showed. Overall, the 5,700 men included in the analysis had a 23% excess mortality from causes other than testicular cancer after treatment with PBCT or RT, as compared […]
Bell’s Palsy After COVID Vaccines Still Very Rare
No significant increased risk of Bell’s palsy was seen after the Pfizer-BioNTech mRNA vaccine, but risk did increase for people who received the CoronaVac (Sinovac Biotech) shot, a vaccine that uses an inactivated virus, an analysis in Hong Kong showed. Compared with the background population, the age-standardized difference for Bell’s palsy incidence was 41.5 (95% […]