Statin Reduced Risk of Heart Disease in People With HIV
BRISBANE, Australia — The cholesterol-lowering agent pitavastatin (Livalo) as primary prevention reduced the risk of major adverse cardiovascular events (MACE) among people living with HIV, the randomized REPRIEVE trial showed. Over a median follow-up of about 5 years, incidence of any MACE was 35% lower in the pitavastatin group compared with a placebo group, at […]
Potential ‘Game Changer’ for Leprosy Prevention
A single dose of rifapentine reduced the incidence of leprosy among household contacts of patients with the infectious disease, a cluster-randomized trial out of China found. In an intention-to-treat analysis, the cumulative incidence of leprosy among 7,450 household contacts was 0.09% with an oral dose of rifapentine over 4 years of follow-up, as compared with […]
Sublingual Vaccine Shows Promise in Women With Recurrent UTIs
CHICAGO — A sublingual vaccine not only reduced the risk of recurrent urinary tract infections (UTIs) in women, it also appeared to enable a significant number of these women to be completely UTI-free, according to a North American study. Among 67 women with three or more UTIs per year, 40.6% of those receiving a 3-month […]
Warning labels on restaurant menus reduced likelihood consumers would order high-sugar foods: But labels should be designed for higher visibility, researchers suggest
Added-sugar warning labels reduced the likelihood that consumers would order items containing high amounts of added sugar in an online experiment led by University of California, Davis, researchers. Menu labels can help inform consumers about the surprisingly high amount of added sugar in even the smallest sizes of soda or in unexpected items like salad […]
Simulated Driver Training May Reduce Accidents Among Teens With ADHD
A simulated driving program reduced inattention and risk of crashing among teens with attention deficit-hyperactivity disorder (ADHD) compared with conventional driver’s training, according to a small study that used a program combining computer-based and driving simulator training. During 15-minute simulated drives, teens in the training group had a mean of 16.5 long glances (>2 seconds) […]
Shaking less salt on your food at the table could reduce heart disease risk: Researchers found a link between a lower frequency of dietary salt and a reduced CVD risk
Adding additional salt to foods at a lower frequency is associated with a reduced risk of heart disease, heart failure and ischemic heart disease, according to a new study published today in the Journal of the American College of Cardiology. Even among those following a DASH-style diet, behavioral interventions to lessen salt consumption could further […]
RT After Breast-Conserving Surgery Shows No Survival Advantage Decades Later
Radiotherapy after breast-conserving surgery for early breast cancer substantially reduced the risk of disease recurrence, yet the benefit did not translate to an improvement in overall survival (OS) at 30 years, a long-term analysis of the Scottish breast conservation trial showed. Compared with no radiotherapy, adjuvant locoregional radiotherapy reduced the risk of ipsilateral breast tumor […]
Want a Few Weeks of Knee Pain Relief? Try This
PHILADELPHIA — Blocking agents delivered to genicular nerves around the knee markedly reduced osteoarthritis patients’ perceptions of pain, far more than those receiving placebo injections, a randomized trial showed. At week 4 following the injections, patients in the nerve block group reported mean reductions in pain scores of 3.0 points from baseline on a standard […]
Treatment De-Escalation Shows Promise in Testicular Cancer
A reduced dose of chemotherapy and involved node radiotherapy (INRT) may be viable for patients with stage IIA or IIB seminoma of the testis, results from a phase II study suggested. In a group of 116 patients, a single-dose of carboplatin along with de-escalated INRT yielded a 3-year progression-free survival (PFS) rate of 93.7% (90% […]
Acupuncture May Help Reduce Urinary Incontinence Episodes, Symptoms in Women
Acupuncture reduced episodes and symptoms of urinary incontinence in women, according to a meta-analysis of 10 clinical studies. Various forms of acupuncture significantly reduced episodes of stress urinary incontinence (SUI, P<0.00001), episodes and symptoms of urge urinary incontinence (UUI, P=0.01 to P<0.0001), and resulted in higher rates of patient-reported SUI cure (P=0.0007). The benefits came […]