No evidence that physical activity calorie-equivalent labelling changes food purchasing
An experiment carried out across ten workplace cafeterias found no significant change in the overall number of calories purchased when food and drink labels showed the amount of physical activity required to burn off their calories. More than three in five UK adults are overweight or obese, increasing their risk of diseases such as type […]
Survival No Better With Intensive Surveillance in Endometrial Cancer
An intensive surveillance regimen for endometrial cancer did not improve overall survival (OS) over a minimalist regimen, even in high-risk patients, results from the randomized TOTEM trial showed. After a median follow-up of 69 months, the 5-year OS rate was 90.6% with the intensive approach versus 91.9% with the minimalist approach, which mainly included physical […]
‘Potential Detrimental Effect’ With Fourth-Line Olaparib in Ovarian Cancer
NEW YORK — A post-hoc analysis of overall survival (OS) in the SOLO3 trial demonstrated why olaparib (Lynparza) recently had its fourth-line indication in ovarian cancer pulled by drugmaker AstraZeneca. The phase III trial, which tested olaparib versus non-platinum chemotherapy for women with BRCA-mutated platinum-sensitive relapsed disease, found diverging OS signals based on whether women […]
Maintenance PARP Inhibition Boosts OS in Two Ovarian Cancer Trials
PARIS — Olaparib (Lynparza) maintenance therapy appears to offer a long-term overall survival (OS) benefit for women with ovarian cancer, according to two phase III studies presented at the European Society for Medical Oncology (ESMO) annual congress. At 7 years in the SOLO-1 trial, 67% of patients with advanced BRCA-mutated ovarian cancer treated with the […]
‘Nutri-Score’ label may counter misleading sugar claims on groceries, analysis suggests: Consumer survey supports the use of Nutri-Score labeling to help boost public health
A new analysis suggests that the Nutri-Score — a label indicating the overall nutritional quality of a food product — can counteract the misleading effects of sugar claims. Kristin Jürkenbeck and colleagues of the University of Göttingent, Germany, present these findings in the open-access journal PLOS ONE on August 17, 2022. High consumption of sugar […]
Increased Public Assistance Tied to Better Cancer Survival in Black Patients
CHICAGO — Overall survival (OS) in Black patients with cancer improved significantly, and racial disparities in cancer survival decreased, with increased state-level spending on public welfare programs, a large retrospective review showed. Every 10% increase in public welfare spending was associated with an 8.6% improvement in cancer survival among Black patients, almost four times greater […]
Guillain-Barre Risk After COVID-19 Vaccines Low, Surveillance Data Show
Risk of Guillain-Barré syndrome after COVID-19 vaccines was low overall, but unusually high after the Johnson & Johnson shot, surveillance data showed. Among 15.1 million doses of COVID-19 vaccines included in the Vaccine Safety Datalink, the unadjusted incidence rate of confirmed Guillain-Barré syndrome 1 to 21 days after receiving the Johnson & Johnson vaccine was […]
Wearing dentures may affect a person’s nutrition: First study to report results of matched health and dental records to assess nutrition levels
Dentures may have a potentially negative impact on a person’s overall nutrition, according to new research from Regenstrief Institute and Indiana University School of Dentistry. The research team leveraged electronic dental and health records to gain a better understanding of how oral health treatments affect individuals’ overall health over time. This is believed to be […]
Adjuvant Chemo Disappoints in Low-Grade Serous Ovarian Cancer
PHOENIX — Adjuvant chemotherapy was not associated with better overall survival (OS) for patients with advanced stage low-grade serous ovarian carcinoma undergoing primary cytoreductive surgery, according to an observational study presented here. There was no difference in OS between patients who did and did not receive adjuvant chemotherapy, with 4-year OS rates of 77.5% and […]
Brain Volumes Shrink With One Daily Drink
Light to moderate alcohol consumption — as few as one or two drinks a day — was linked with reductions in overall brain volume, a cross-sectional study showed. Among nearly 37,000 healthy adults in the U.K. Biobank, alcohol intake was negatively associated with global brain volume measures, regional gray matter volumes, and white matter microstructure, […]