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Primary Care Strategy Fails to Reduce Kidney-Dysfunction Triad Hospitalizations

Using a personalized algorithm to identify primary care patients with chronic kidney disease (CKD), type 2 diabetes, and hypertension (the kidney-dysfunction triad) — plus practice facilitators to help providers deliver guideline-based interventions — didn’t move the needle for reducing hospitalizations, the ICD-Pieces study found. At 1 year, the hospitalization rate of patients in the intervention […]

U.S. Surgeons Transplant Gene-Edited Pig Kidney Into A Patient For The First Time

Surgeons remove a gene-edited transplanted pig kidney from the body of Maurice “Mo” Miller at NYU Langone Health in New York on Sept. 13, 2023. For a history-making 61 days and despite a brief rejection blip, a pig’s kidney worked normally inside his brain-dead body. AP Photo/Shelby Lum NEW YORK (AP) — Doctors in Boston […]

Immunotherapy May Hold Promise for Skin Cancers After Kidney Transplant

The use of immune checkpoint inhibitors given as part of an immunosuppressive regimen for kidney transplant recipients with advanced cutaneous cancers may be effective and safe, depending on the regimen, two small studies suggested. In the first study among 12 kidney transplant recipients with advanced cutaneous squamous cell carcinoma (CSCC) who were treated with cemiplimab […]

One Class of Antidiabetic Linked With Lower Kidney Stone Risk

One class of glucose-lowering agent may help lower the risk of kidney stones in adults with type 2 diabetes, a cohort study suggested. Adults who newly started on an SGLT2 inhibitor had a 31% lower risk of nephrolithiasis compared with those starting on a GLP-1 receptor agonist (HR 0.69, 95% CI 0.67-0.72), found Julie M. […]

Methotrexate Tied to Greater Risks for Older Patients With CKD

Older patients with chronic kidney disease (CKD) had greater risks for serious adverse events when starting on low-dose methotrexate rather than hydroxychloroquine, a propensity score-matched analysis found. About 60% of the cohort’s new prescription came from a rheumatologist. Within 90 days of starting either treatment, the risk for the composite outcome — a hospital visit […]

Sugar-Heavy Diet Linked to Development of Kidney Stones

A diet high in added sugars may predispose people to developing kidney stones, a nationally representative study suggested. In an analysis of over 28,000 U.S. adults, those who consumed the most energy from added sugars had 39% higher odds of developing kidney stones compared with those who consumed the least amount of added sugars (OR […]

AKI Cleared of Worsening CKD Trajectory

Acute kidney injury (AKI) didn’t predict worsening kidney function in people with chronic kidney disease (CKD), a prospective study showed. According to findings from the Chronic Renal Insufficiency Cohort (CRIC) study, CKD patients hospitalized for AKI saw a statistically insignificant drop in estimated glomerular filtration rate (eGFR) during a nearly 4-year follow-up period, reported Chi-yuan […]

Massive Kidney Stone Sets New Record

Surgeons in Sri Lanka have removed the largest and heaviest kidney stone on record from a 62-year-old patient, according to Guinness World Records. The stone measured 5.26 inches in length and 4.15 inches in width, and weighed in at 1.76 pounds, according to the publication. It broke the previous size record, set in 2004 when […]

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