Fatty food before surgery may impair memory in old, young adults
Eating fatty food in the days leading up to surgery may prompt a heightened inflammatory response in the brain that interferes for weeks with memory-related cognitive function in older adults — and, new research in animals suggests, even in young adults. The study, building upon previous research from the same lab at The Ohio State […]
Another Study Backs Treatment for Preclinical Rheumatoid Arthritis
Inflammatory markers were reduced in patients with persistent joint pain and other markers for incipient rheumatoid arthritis (RA), as was progression to formal RA diagnosis, after a 6-month course of abatacept (Orencia) in a placebo-controlled trial. While 35% of controls were diagnosed with RA while on treatment in the trial, called ARIAA, only 8% of […]
Switching Twice With Infliximab Biosimilars Not Linked With IBD Flare Risk
LAS VEGAS — Biosimilar switching was not tied to flare in patients with inflammatory bowel disease (IBD), according to a retrospective cohort study. Patients who switched from infliximab (Remicade) to an infliximab biosimilar, and then switched again to a different biosimilar or back to infliximab, were no more or less likely to experience a disease […]
Could Arthritis Enhance Male Fertility?
Infertility does not seem to be a problem for men with inflammatory joint diseases, a large Scandinavian study indicated. In fact, men with arthritis showed lower rates of childlessness relative to a control group, and had fathered more children on average, according to Gudrun David Sigmo, of Stavanger University Hospital in Norway, and colleagues. National […]
Red Meat Consumption Tied to Higher Chance of UC Flare
ORLANDO – For people with inflammatory bowel disease (IBD), that hamburger may come with more than just a side of fries — red meat consumption was linked with a higher risk for ulcerative colitis (UC) flare, researchers reported. According to an analysis of data from the IBD Partners research, patients with UC who were in […]
National Database Study Finds Higher Risk for Barrett’s Esophagus in IBD
ORLANDO – People with inflammatory bowel disease (IBD) faced higher odds of Barrett’s esophagus (BE) and BE without dysplasia, but not BE-linked malignancy, according to a cross-sectional study. Among patients diagnosed with ulcerative colitis (UC), the prevalence of BE was 0.077%, while the prevalence of BE in patients with Crohn’s disease (CD) came in at […]
Microbiome Study Provides New Clues to Common Pathology of Inflammatory Conditions
An alteration in gut microbiome diversity occurred in patients with three different inflammatory conditions, suggesting a common pathology, prospective rRNA sequencing of patients’ stool samples showed. Patients with axial spondyloarthritis (SpA), acute anterior uveitis (AAU), and Crohn’s disease had a low concentration of Lachnospiraceae compared with a control group of patients with back pain and […]
Benefits of Parathyroidectomy Run Far Deeper Than PTH Normalization
SEATTLE — Parathyroidectomy helped reverse disrupted levels of inflammatory cytokines and vitamin D metabolites in patients with primary hyperparathyroidism (PHPT), a researcher suggested here. After 50 patients, newly diagnosed with PHPT, underwent parathyroidectomy, serum intact parathyroid hormone (PTH) levels returned to the normal range within 3 months (115.6±38.9 to 42.6±24.5 pg/mL, P<0.001), said Xiangbing Wang […]
Wearable Tech Shows Promise for Predicting IBD Flares
DENVER — A smart watch app may help physicians and patients pinpoint and predict inflammatory bowel disease (IBD) flares, researchers reported. When a person with IBD has a normal gut environment, a bell curve is produced by the watch application, explained Robert Hirten, MD, of the Icahn School of Medicine/Susan and Leonard Feinstein Inflammatory Bowel […]
IBD Risk Higher After Antibiotics
Antibiotics were linked with increased risk for inflammatory bowel disease (IBD), especially among individuals 40 or older, in a population-based study conducted in Denmark. Of more than 6 million individuals followed for approximately 19 years, antibiotic use was associated with nearly 50% increased incidence of IBD in people ages 40 to 60 (IRR 1.48, 95% […]