Time for Targeted PSA Screening for Men With Rare Pathogenic Variants?
Men with certain pathogenic variants had a higher incidence of prostate cancer versus age-matched controls, and may be candidates for targeted prostate-specific antigen (PSA) screening, according to findings from the IMPACT trial. In the international, prospective study, men with confirmed pathogenic variants in mismatch repair (MMR) genes who underwent one screening round had a higher […]
How high-fat diets allow cancer cells to go unnoticed
A high-fat diet increases the incidence of colorectal cancer. Cold Spring Harbor Laboratory Fellow Semir Beyaz and collaborators from Harvard Medical School and Massachusetts Institute of Technology have discovered that in mice, fat disrupts the relationship between intestinal cells and the immune cells that patrol them looking for emerging tumors. Reconfiguring the gut microbiome may […]
Masks Limited COVID Transmission in Unvaxxed College Kids
Masking worked, along with fewer exposure encounters, to help limit the incidence of COVID-19 infection among largely unvaccinated university students in Missouri, researchers found. Among nearly 400 close contacts of students who tested positive for SARS-CoV-2, the likelihood of a positive test result was more than five times higher in situations where at least one […]