Pre-Op Atezolizumab Promising in Muscle-Invasive Bladder Cancer
The use of a checkpoint inhibitor combined with chemotherapy in the neoadjuvant setting appeared to be effective for patients with muscle-invasive bladder cancer (MIBC), according to results from a phase II trial. Among 39 patients, the addition of the PD-L1 inhibitor atezolizumab (Tecentriq) to gemcitabine and cisplatin resulted in a non-muscle-invasive downstaging rate of 69% […]
Study explores how temperate rainforests can aid the fight against climate change
There is global recognition that woodland expansion could be one of the most effective solutions in the fight against climate change. However, new research has shown that the level of growth needed to produce the amount of trees required by UK targets is unlikely to be achieved through natural means alone. Environmental scientists and ecologists […]
For children, young adults with recurrent AML, immunotherapy shows promise: Natural killer cells could help young patients with few treatment options
An immunotherapy harnessing the immune system’s “natural killer” cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return. Now, researchers at Washington University School of Medicine in St. Louis have shown, in a small clinical trial, that the same natural killer cells also can help some children and young […]
How Do You Get Rid of Airplane Ears? 7 Home Remedies
7 ways to get rid of airplane ears in adults Here are 7 effective ways to get rid of airplane ears in adults and a few ways to treat them in children. Swallowing: Swallowing is an effective method that activates muscles to open eustachian tubes. Swallowing helps clear blocked ears in children because it is […]
COVID Prevention Tx Safe, Shows Efficacy in High-Risk Groups
A monoclonal antibody cocktail designed for COVID-19 pre-exposure prophylaxis was safe, and appeared to be effective across populations at risk of severe COVID and who may have a subpar response to vaccination, a researcher said. AZD7442 (tixagevimab/cilgavimab) met its primary endpoint, reducing the risk of symptomatic COVID-19 among high-risk populations by 77% (95% CI 46%-90%), […]
Probiotics Show Promise for Symptoms of Functional GI Disorders
Spore-forming probiotics were safe and effective for treating functional dyspepsia symptoms in a small randomized Belgium trial. In an intention-to-treat analysis involving 55 patients with functional dyspepsia, a greater proportion of those given probiotics achieved clinical response at 8 weeks compared to patients given placebo (48% vs 20%, respectively; RR 1.95, 95% CI 1.07-4.11, P=0.028), […]
Less-Invasive Tibial Nerve Stimulator Quiets Overactive Bladder
A minimally invasive, coin-sized implantable device was effective in treating overactive bladder (OAB) syndrome, researchers found. In a prospective, single-arm, open-label study funded by the device’s manufacturer, the novel, leadless tibial nerve stimulator achieved at least a 50% reduction in urgency urinary incontinence in two-thirds of the patients, reported Alexandra Rogers, MD, of Sansum Clinic […]
Vascular Function: Another Benefit of Bariatric Surgery
Beyond weight loss, bariatric surgery was also effective at improving vascular outcomes, a new study found. In a study of more than 300 adults with obesity, there was an average 17.5% loss of initial body weight during a roughly 6-month follow-up period after undergoing bariatric surgery, reported Noyan Gokce, MD, of Boston Medical Center in […]