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Sacral Neuromodulation Promising in Neurogenic Lower Urinary Dysfunction

Sacral neuromodulation (SNM) is effective — at least in the short term — for patients with a type of urinary tract dysfunction, according to Swiss investigators. In a sham-controlled, double-blind study, 60 eligible patients with neurogenic lower urinary tract dysfunction (NLUTD) — i.e., with urgency frequency syndrome, urgency incontinence, or chronic urinary retention — had […]

MRI-Guided HIFU Effective in Intermediate-Risk Prostate Cancer

MRI-guided high-intensity focused ultrasound (HIFU) is effective in patients with intermediate-risk prostate cancer, researchers reported. According to the team’s multicenter, single-arm, phase IIb study of 101 patients who received the treatment, 96% had no evidence of grade group 2 or higher prostate cancer on 6-month MRI-targeted and systematic biopsy in the treated area of the […]

COVID mRNA Vaccines Safe, Effective for Babies and Toddlers, Says FDA Staff

Moderna and Pfizer/BioNTech’s COVID-19 vaccines proved safe and effective for kids under 5 years of age, paving the way for immunization of the only age group still awaiting access, according to FDA briefing documents released ahead of 2 days of advisory meetings. On Tuesday, the Vaccines and Related Biological Products Advisory Committee (VRBPAC) will meet […]

Brentuximab Vedotin-Chemo Boosts EFS in High-Risk Pediatric Hodgkin Lymphoma

CHICAGO — A combination of brentuximab vedotin (Adcetris) and chemotherapy was safe and effective in pediatric patients (up to age 21 years) with newly diagnosed high-risk Hodgkin lymphoma, a researcher reported here. In the phase III study, a regimen of brentuximab vedotin (Bv) combined with doxorubicin, vincristine, etoposide, prednisone, and cyclophosphamide chemotherapy (AVE-PC) was superior […]

T-Cell Receptor Gene Therapy Shows Promise in Pancreatic Cancer

A novel T-cell receptor (TCR) gene therapy may be effective in treating patients with pancreatic cancer and other cancers that express the KRAS G12D mutation, researchers have found. Their case study — published in the New England Journal of Medicine (NEJM) — showed that a heavily pretreated patient with pancreatic ductal adenocarcinoma achieved a deep […]

Organic farming or flower strips: Which is better for bees?

How effective environmental measures in agriculture are for biodiversity and wild bee populations depends on various factors and your perspective. This is shown by agroecologists from the University of Göttingen, Germany and the Centre for Ecological Research in Vácrátót, Hungary. The research team found that when assessing the effectiveness of different measures, whether in the […]

Vaginal Estrogen ‘Underutilized’ in Women With GSM After Breast Cancer

NEW ORLEANS — While vaginal estrogen therapy is safe and effective for genitourinary syndrome of menopause (GSM), few women who have had breast cancer use it, researchers reported here. Breast cancer survivors with GSM were half as likely to be prescribed vaginal estrogen compared to women with GSM and no history of breast cancer (11% […]

Opinion | Can Antivirals Help in the Treatment of Long COVID?

Let me begin by stating some basic emerging facts: COVID-19 vaccines are highly effective in combating COVID-associated mortality COVID-19 vaccines may reduce the risk of getting long COVID by 50% Of all people who get infected with COVID-19 after vaccination, 15-30% will develop long COVID There is no sufficient evidence to show COVID-19 vaccines help […]

5 Most Effective Drug Addiction Treatments: Substance Abuse

5 most effective drug addiction treatments The most effective drug addiction therapies combine behavioral therapy and medications that are personalized to the patient’s needs. The most effective drug addiction therapies combine behavioral therapy and medications that are personalized to the patient’s needs and, in the long term, avoid relapse. The finest treatments are tailored to […]

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