Babies Fare Better If Gestational Diabetes Is Treated Early in Second Trimester
Treating gestational diabetes early in pregnancy without waiting for confirmation of a repeat oral glucose-tolerance test (OGTT) improved neonatal outcomes, the TOBOGM randomized trial showed. For women first diagnosed before 20 weeks’ gestation, immediate treatment significantly reduced the composite incidence of adverse neonatal outcomes — preterm birth, birth trauma, high birth weight, respiratory distress, phototherapy, […]
E-Cigs in Early Adolescence Tied to Heavier Smoking Later On
Use of electronic cigarettes during early adolescence appeared to increase the odds of any smoking and more frequent tobacco cigarette use in later adolescence, according to longitudinal data from two large-scale cohorts in the U.K. and U.S. Among youths who began smoking before age 15, the odds of later adolescent smoking were significantly higher for […]
Fasting diet reduces risk markers of type 2 diabetes
A fasting diet which focuses on eating early in the day could be the key to reducing the risk of developing type 2 diabetes. Researchers from the University of Adelaide and South Australian Health and Medical Research Institute (SAHMRI) compared two different diets: a time restricted, intermittent fasting diet and a reduced calorie diet to […]
What Drives Alzheimer’s in Women?
Female sex, early age at menopause, and hormone therapy use each were associated with higher regional tau in cognitively normal people with elevated beta-amyloid, cross-sectional PET data showed. The highest levels of tau were seen in hormone therapy users who had a delay of more than 5 years between menopause onset and the start of […]
Early LRTIs Tied to Risk of Premature Adult Death From Respiratory Diseases
A lower respiratory tract infection (LRTI) in early childhood nearly doubles the risk of premature death from respiratory diseases in adulthood, according to a prospective cohort study that spanned eight decades. The study of over 3,500 individuals born in the U.K. found that participants diagnosed with an LRTI by age 2 years were 93% more […]
What Next After Early End of MOSAICO HIV Vaccine Trial?
SEATTLE — The abrupt and early end of the MOSAICO HIV vaccine trial, announced last month, was the topic of a special session at the Conference on Retroviruses and Opportunistic Infections here. Results of the 3,800-participant trial were negative, with an identical 113 individuals in the vaccine regimen and placebo groups becoming infected with HIV […]
Researchers link 27 genetic variants to ADHD
Why do some people get ADHD, while others do not? And how early in life or in the womb is the seed of ADHD sown? Researchers from Aarhus University have come closer to answering this question in a large study, which has just been published in the journal Nature Genetics. Together with national and international […]
Short-Course Apalutamide to Reduce Active Surveillance Attrition in Prostate Cancer
A majority of men in active surveillance (AS) for early prostate cancer had negative biopsies after a 90-day course of apalutamide (Erleada), a small phase II trial showed. Follow-up pathology showed no evidence of residual cancer in 13 of 22 evaluable patients following treatment with the androgen receptor inhibitor. The median time to a positive […]
CDC, FDA Flag Early Signal of Stroke Risk With Bivalent COVID Vaccine
An early signal of stroke risk was detected in older adults who received Pfizer-BioNTech’s bivalent COVID-19 vaccine, the FDA and CDC announced in a joint statement late on Friday, yet the agencies found no link in further analyses and are not recommending a change in COVID-19 vaccination practice. According to the agencies, incidence of ischemic […]
For People With HIV, Early Anal Cancer Screening Tied to Better Outcomes
Screening HIV-positive individuals for early signs of anal cancer may lead to an earlier diagnosis and better survival, according to an observational Dutch cohort study. Among men who have sex with men (MSM) living with HIV, anal cancer-related mortality was 3.7% in those who had been screened in the Netherlands compared with 24.0% in those […]