Low-Dose Semaglutide Can Ease Insulin Need in Early T1D, Small Series Shows
When used very early on in type 1 diabetes, a GLP-1 receptor agonist may help reduce the need for insulin, a small case series suggested. Ten adults with a new type 1 diabetes diagnosis initially received a 0.125-mg dose of weekly semaglutide (Ozempic), which was adjusted up to a maximum of 0.5 mg per week […]
Few Early Alzheimer’s Patients Qualify for Lecanemab
Few people with early Alzheimer’s disease met eligibility criteria for the new anti-amyloid monoclonal antibody treatments lecanemab (Leqembi) and aducanumab (Aduhelm), cross-sectional data from the Mayo Clinic Study of Aging showed. Of 237 people with mild cognitive impairment or mild dementia and increased brain amyloid on PET, clinical trial inclusion and exclusion criteria narrowed the […]
A mother’s diet can protect her grandchildren’s brains: genetic model study
Mothers who eat apples and herbs in early pregnancy could be protecting the brain health of their children and grandchildren, a Monash University study using genetic models has found. The discovery is part of a project that found a mother’s diet can affect not just her child’s brain but also those of her grandchildren. Published […]
External Causes of Death More Likely in Those With Bipolar Disorder
While bipolar disorder is known to be associated with early mortality, deaths are more likely to be caused by external factors, such as suicide, than somatic factors, such as alcohol-related diseases, according to a Finnish nationwide cohort study. In the cohort of people ages 15 to 64, those with bipolar disorder had six-fold higher mortality […]
Fired COVID Whistleblower Will Take His Case to Trial With New Lawyers
Ming Lin, MD, the emergency physician who was fired early in the COVID pandemic for airing alleged safety concerns, has hired new lawyers to take his case to trial. After parting ways with lawyers working for the American Civil Liberties Union (ACLU) because he didn’t want to settle his case as they recommended, Lin selected […]
Opinion | The Straw-Man Argument Against California’s COVID Misinfo Law
Sawyer is an emergency medicine doctor. An article in the South Carolina Post and Courier in early 2022 recounts how a patient levied grave accusations against his physician. The doctor was accused of persistently trivializing the dangers of COVID, recommending hydroxychloroquine as treatment, and purportedly alleging that the vaccines were concocted as a sinister plot […]
Subclinical CVD Detected in Kids With Higher Arsenic Burden
Greater arsenic exposure was linked to children harboring subclinical cardiovascular disease (CVD) as early as age 9, based on data from Syracuse, New York. In this upstate community with a history of industrial waste, total arsenic level significantly correlated with carotid intima media thickness and concentric hypertrophy (the latter indicated by greater left ventricular mass […]
Early Time-Restricted Eating Cut Blood Sugar Fluctuations in Prediabetes
CHICAGO – Just 1 week of early time-restricted feeding (eTRF) cut fluctuations in blood sugar levels, and reduced the time that blood sugar was elevated, in people with prediabetes and a high BMI, according to the TRIO study. The difference in the mean amplitude of glycemic excursion (MAGE) — the standard for assessing short-term within-day […]
How To Protect Kids When The Air Quality Is Terrible
In these warm early days of summer, parks are generally filled with kids playing through the long daylight hours. But right now, in a dark echo of the pandemic, schoolyards and playgrounds throughout the Northeastern U.S. sit empty. N-95 masks are again in high demand as air quality remains “unhealthy” and even “hazardous” with the […]
Multimodal Evaluations May Flag Cardiac Allograft Problems Earlier
Coronary anatomy and physiology both predicted early cardiac allograft vasculopathy (CAV) progression, according to a study that strengthens the case for advanced multimodal testing to improve early detection of a major contributor to allograft failure. Among heart transplant recipients at two Canadian centers, early progression of percent intimal volume (PIV) on intravascular ultrasound (IVUS) between […]