Allergy Meds May Make Drug Overdoses More Dangerous, CDC Says
Antihistamines were involved in at least 15% of recent overdose deaths, according to 2019-2020 data from 43 states and the District of Columbia. Of 92,033 overdose deaths during this time period, 14.7% were antihistamine-positive and 3.6% were antihistamine-involved, reported Amanda Dinwiddie, MPH, of the CDC’s National Center for Injury Prevention and Control in Atlanta, and […]
Opinion | ‘I Really Feel We Need the Human Data’: What We Heard This Week
“I really feel we need the human data.” — Pablo Sanchez, MD, of the CDC’s Advisory Committee on Immunization Practices, who cast the only vote against recommending the new bivalent boosters due to the lack of clinical trial data. “It could cause a lot of anxiety in people.” — Sean McGann, MD, an emergency physician […]
Durable Remissions in CLL With Fixed-Duration Triplet at 4 Years
Four-year follow-up data from a phase II study evaluating obinutuzumab (Gazyva), ibrutinib (Imbruvica), and venetoclax (Venclexta) in patients with chronic lymphocytic leukemia (CLL) were presented at the American Society of Clinical Oncology annual meeting. In this exclusive MedPage Today video, Kerry Rogers, MD, of the Ohio State University Comprehensive Cancer Center in Columbus, discusses the […]
Gaia space telescope rocks the science of asteroids
The European Gaia space mission has produced an unprecedented amount of new, improved, and detailed data for almost two billion objects in the Milky Way galaxy and the surrounding cosmos. The Gaia Data Release 3 on Monday revolutionizes our knowledge of the Solar System and the Milky Way and its satellite galaxies. The Gaia space […]
Astronomers find evidence for most powerful pulsar in distant galaxy
Astronomers analyzing data from the VLA Sky Survey (VLASS) have discovered one of the youngest known neutron stars — the superdense remnant of a massive star that exploded as a supernova. Images from the National Science Foundation’s Karl G. Jansky Very Large Array (VLA) indicate that bright radio emission powered by the spinning pulsar’s magnetic […]
Immunotherapy Rechallenge in NSCLC Yields Overall Survival Boost
CHICAGO — Randomized data suggest that an anti-angiogenic agent can kick-start immunotherapy’s antitumor activity in non-small cell lung cancer (NSCLC) patients whose disease has already progressed after chemotherapy and a checkpoint inhibitor. In the phase II study, median overall survival improved by nearly 3 months with ramucirumab (Cyramza) plus pembrolizumab (Keytruda) versus standard-of-care options (14.5 […]
Genetic links revealed between severe COVID-19 and other diseases: Large-scale study could help inform novel COVID-19 treatment strategies
A new analysis of data from the Veterans Affairs Million Veteran Program has uncovered genetic links between COVID-19 severity and certain medical conditions that are known risk factors for severe COVID-19. Anurag Verma of the Corporal Michael Crescenz VA Medical Center in Philadelphia, Pennsylvania, US, and colleagues present these findings on April 28 in the […]
Smartwatches and fitness bands reveal individual physiological responses to COVID-19 vaccine: Scientists find digital biomarkers that could be associated with vaccine-induced immune response
A new digital health study by researchers at Scripps Research shows how data from wearable sensors, such as smartwatches and fitness bands, can track a person’s physiological response to the COVID-19 vaccination. The study, published in npj Digital Medicine, analyzed sensor data on sleep, activity and heart rate from over 5,600 individuals. Among the findings, […]
ALS Drug Needs More Evidence, FDA Advisors Say
In a close call, an FDA advisory committee said data from a single trial for AMX0035, an investigational agent being studied to treat amyotrophic lateral sclerosis (ALS), did not support a conclusion that the drug was effective. The 6-4 vote of the Peripheral and Central Nervous System Drugs Advisory Committee was based on findings from […]
Opinion | ‘This Is Probably the Most Obviously Fake Data I Have Seen’: What We Heard This Week
“This is probably the most obviously fake data I have seen.” — Kyle Sheldrick, MBBS, PhD candidate at the University of New South Wales, on the potentially fraudulent data underpinning an infamous study of vitamin C for sepsis. “It is OK to have financial relationships with industry.” — Adam Bitterman, DO, of Northwell Health Physician […]