Cardiorespiratory Monitoring Can Be Telling of Outcomes in Extremely Preterm Infants
Physiologic data from cardiorespiratory monitoring may provide prognostic information about the clinical outcomes of extremely preterm infants, the Prematurity-Related Ventilatory Control (Pre-Vent) study found. The endpoint of death or need for respiratory medications or support at 40 weeks postmenstrual age (PMA) was predicted by physiological parameters, the relationship growing stronger as the babies got older, […]
Lifestyle Factors and Glaucoma: Lots of Common Sense, Not So Much Evidence
SAN DIEGO — Limited data support a role for lifestyle factors in the prevention or management of glaucoma, according to a review presented here. Intuitively, diet, mental health, and good posture should contribute to good eye health, but the evidence does not support the intuition. Despite the dearth of positive studies, a better-safe-than-sorry approach remains […]
Behavior patterns of people who achieve clinically significant weight loss: Study finds widespread poor adoption of heart-healthy measures in US adults
A new study analyzing data on over 20,000 U.S. adults links a healthier diet and increased exercise to weight loss that reduces heart disease risk — while associating skipping meals and taking prescription diet pills with minimal weight loss, weight maintenance or weight gain. For many in the study sample, however, losing a “clinically significant” […]
Cluster Headache, Migraine Linked to Circadian System
Cluster headache and migraine were linked to the circadian system, data from a meta-analysis and other research showed. Across 16 studies, cluster headache had a prominent circadian pattern of attacks in 70.5% of 4,953 participants, with a clear peak between 21:00 and 03:00 and circannual peaks in the spring and autumn, reported Mark Joseph Burish, […]
CDC Offers Tentative Guidance for Severe Mpox Treatment
With no clinical trial data yet available for treating severe mpox, the CDC has published an interim report with guidance. There are many FDA-regulated drugs and biologics stockpiled for smallpox preparedness that can be used to treat severe mpox; however, there are many clinical considerations when using these to help manage strategic decision-making, the CDC […]
Fewer Emergency Department Visits End With Opioid Prescriptions
Fewer emergency department (ED) visits end with a prescription for opioids, CDC survey data showed. The percentage of ED visits with an opioid prescribed at discharge fell from 12.2% in 2017-2018 to 8.1% in 2019-2020, reported Loredana Santo, MD, MPH, and Susan Schappert, MA, of the National Center for Health Statistics in Hyattsville, Maryland, in […]
Opinion | ‘Is This an Underestimate of the Harm?’: What We Heard This Week
“Is this an underestimate of the harm?” — Martin J. Landray, PhD, of the University of Oxford in England, on preprint data from the RECOVERY trial showing higher corticosteroid doses raised the risk of death in non-ventilated COVID-19 patients with hypoxia. “I was talking to some other doctors about it online, and there was a […]
Parkinson’s Incidence 50% Higher Than Previously Thought
The annual incidence of Parkinson’s disease was 50% higher than previous estimates in data from five epidemiological cohorts in the U.S. and Canada. The new incidence rate was nearly 90,000 cases annually for people 65 and older, reported Allison Willis, MD, of the University of Pennsylvania in Philadelphia, and co-authors. This contrasted sharply with the […]
Second Trial Participant Dies in Alzheimer’s Drug Study
Days before the release of promising phase III trial data of lecanemab, an investigational anti-amyloid drug for early Alzheimer’s disease, a death possibly linked to the treatment was reported. An unpublished case report featured in Science suggested the death of a 65-year-old lecanemab trial participant who also had cerebral amyloid angiopathy — a condition in […]
Lack of access to healthy food may raise risk of death from heart failure
A study reviewing data from nearly 3,000 counties in the United States has found that living in a community with easy access to grocery stores and affordable, healthy food is associated with lower heart failure death rates, according to new research published today in Circulation: Heart Failure, an American Heart Association journal. Food insecurity occurs […]