Bempedoic Acid Gets ‘Huge’ Win for Primary Prevention in the Statin-Intolerant
SAN DIEGO — Bempedoic acid (Nexletol) prevented cardiovascular events in high-risk, statin-intolerant patients who had not yet had an event, a subgroup analysis from the CLEAR Outcomes trial confirmed. In these patients, bempedoic acid was associated with a large decrease in risk of major adverse cardiovascular events (MACE) compared with placebo over a median 39.9 […]
Americans With Heart Disease Less Likely to Use Wearable Devices
Fewer Americans with or at risk for cardiovascular disease (CVD) used a wearable health monitoring device than the general population, according to a nationally representative sample using 2019-2020 Health Information National Trends Survey (HINTS) data. Only 18% of adults with CVD and 26% of those at risk for CVD reported using a wearable device to […]
Obesity-Related Medication Use Remains Low After Bariatric Surgery
Fewer patients with obesity used lipid-lowering, cardiovascular, or antidiabetic drugs after bariatric surgery compared with matched patients who did not have surgery for morbid obesity, a population-based cohort study in Sweden and Finland found. Bariatric surgery patients had a lower probability of receiving a prescription for one of the three categories of medication in all […]
GLP-1 Agonists Come Out on Top in Cardiovascular Comparison of Newer Diabetes Meds
Diabetes patients adding a newcomer drug to their medications may derive cardiovascular benefits to varying degrees depending on their choice between GLP-1 agonists and SGLT-2 inhibitors, a large observational dataset suggested. Among U.S. veterans already on metformin, sulfonylurea, or insulin treatment and without cardiovascular disease (CVD), the addition of a GLP-1 agonist, instead of a […]
Erectile Dysfunction Drugs May Have Major Cardiovascular Benefits
CHICAGO — The two most popular medications for erectile dysfunction (ED) may confer substantial cardiovascular benefits for men with ED and concurrent heart disease, according to an analysis of a health research database. Both sildenafil and tadalafil significantly reduced the likelihood of progression to heart failure, myocardial infarction (MI), and death after 5 years as […]
People with obesity due to genetic predisposition have lower risk of cardiovascular disease
The risk of developing cardiovascular disease is lower in people with obesity who have a genetic predisposition for high BMI than people with obesity influenced mainly by environmental factors such as lifestyle, researchers from Karolinska Institutet report in eClinicalMedicine. There has been a global increase in the incidence of overweight and obesity over the past […]
Women With Hypertension During Pregnancy Face Higher CVD Risks
Women with hypertensive disorders of pregnancy (HDP) were at a significant risk for developing new cardiovascular disease (CVD) within a couple of years of giving birth, a researcher reported. Within 2 years postpartum, patients with HDP had almost two times the risk for cerebrovascular disease, nearly three times the risk for cardiomyopathy and heart failure […]
Drinking 2 or more cups of coffee daily may double risk of heart death in people with severe hypertension: Green tea, in contrast, did not increase mortality risk at any blood pressure level
Drinking two or more cups of coffee a day may double the risk of death from cardiovascular disease among people with severe high blood pressure (160/100 mm Hg or higher) but not people with high blood pressure not considered severe, according to research published today in the Journal of the American Heart Association, an open […]
Green tea extract may harm liver in people with certain genetic variations
Long-term use of high-dose green tea extract may provide some protection against cancer, cardiovascular disease, obesity and type 2 diabetes, but it also may create liver damage in a small minority of the population. Who is at risk? Research from Rutgers, published in The Journal of Dietary Supplements, provides the first solid clue: two genetic […]
Diet and exercise for obese mothers protects cardiovascular risk in infants
A lifestyle intervention of diet and exercise in pregnancy protects against cardiovascular risk in infants, a new study has found. The study, published recently in the International Journal of Obesity by researchers from King’s College London and funded by the British Heart Foundation, found that 3-year-old children were more likely to exhibit risk factors for […]