Methenamine Hippurate Could Be Alternative Treatment for Recurrent UTI
The urinary antiseptic methenamine hippurate (Hiprex) was non-inferior to antibiotic prophylaxis in women with a history of recurrent urinary tract infections (UTI), according to results from the ALTAR trial. Over the course of 12 months, the incidence of antibiotic-treated UTI was 0.89 and 1.38 episodes per year in patients treated with prophylactic antibiotics or methenamine […]
Can we save more lives if we let resistant bacteria live?
Antibiotic resistance is a ticking bomb under public health. WHO predicts that in 2050 more people will die from infections than from cancer — and we are talking about infections that we today consider harmless; infections that occur in a cut or wound — or perhaps cystitis. The reason is that bacteria are masters at […]
Is MRSA Contagious? Transmission, Signs & Symptoms
Linezolid (generic name), brand name Zyvox, is a man-made (synthetic) antibiotic that is prescribed for the treatment of a variety of bacterial infections, for example: Pneumonia and uncomplicated skin and structure infections caused by Staphylococcus Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus agalactiae bacteria. Vancomycin-resistant Enterococcus faecium bacterial infections. Common side effects include of linezolid: Constipation […]
Antibiotics Slow Down Latent Rheumatic Heart Disease in Kids
Antibiotic prophylaxis for screen-detected latent rheumatic heart disease reduced progression of disease in children, the GOAL trial showed. Echocardiographic progression was reduced to 0.8% at 2 years compared with 8.2% with no prophylaxis (P<0.001), reported Andrea Beaton, MD, of Cincinnati Children’s Hospital Medical Center, at the American Heart Association virtual meeting. The findings were simultaneously […]
Antibiotic Could Thwart Costly Sarcoma Surgery Complication
BALTIMORE — Including an antibiotic with strong activity against anaerobic bacteria to standard perioperative prophylaxis following soft-tissue sarcoma (STS) resection was associated with lower wound complication rates, a retrospective study suggested. Overall, major wound complication rates dropped from 27.3% to 15.9% when an antibiotic such as metronidazole was incorporated into perioperative prophylaxis, a 42% relative […]
Drug-resistant bacteria found in the guts of lemurs who live around humans: The more human interaction they had, the higher the proportion of resistant bugs
Antibiotic resistance, which the CDC calls one of the world’s most urgent public health crises, is now being found in the guts of lemurs, our distant primate cousins. In a new study appearing Aug. 9 in the journal Frontiers in Ecology and Evolution, Duke researchers have found evidence for antibiotic resistance in the microbiome of […]
Can Education Tackle Poor Antibiotic Prescribing in Nursing Homes?
An educational intervention to cut inappropriate antibiotic use for suspected urinary tract infections (UTIs) and lower respiratory tract infections among nursing home residents with advanced dementia had a limited impact in a cluster randomized trial. The multicomponent TRAIN-AD intervention reduced such prescribing by 33% per person-year compared with usual care (adjusted marginal rate difference −0.27, […]