A microRNA network is the putative mediator of reductive stress in the heart: Understanding how reductive stress is controlled may help personalize treatment of heart failure patients, leading to better outcomes
Last year, University of Alabama at Birmingham researchers reported that reductive stress — an imbalance in the normal oxidation/reduction homeostasis — caused pathological changes associated with heart failure in a mouse model. This was a follow-up to their 2018 clinical study that about one in six heart failure patients shows reductive stress. Now, in the […]
Start Rhythm Control Early for Afib With Heart Failure
Tackling rhythm control early, with ablation or antiarrhythmic medication in the first year after atrial fibrillation (Afib) diagnosis, helped outcomes in people with heart failure (HF), a prespecified subanalysis of the EAST-AFNET 4 trial showed. The early strategy cut the composite of cardiovascular death, stroke, or hospitalization for worsening HF or for acute coronary syndrome […]
A Medical Resident’s COVID-19 Diary
[embedded content] Siobhan Deshauer, MD, recounts the past year and a half, from working in the emergency department and caring for critically ill patients in the ICU, to getting sick with COVID herself, finally getting vaccinated, and giving out vaccinations to others. Deshauer: Hey, guys. I’m Siobhan, a fifth-year medical resident. Now, today’s video is […]
Inside Olympic Precautions: Three Team Doctors Dish
While the Olympic games were cancelled due to the pandemic last year, Japan and host city Tokyo ironically are experiencing higher COVID-19 case numbers than last summer, with a 7-day average of about 5,000 cases. To mitigate spread, the Olympics are ‘bubbled’ and devoid of fans. So how are precautions playing out on the ground? […]
A promising new pathway to treating type 2 diabetes
This year marks the 100th anniversary of the discovery of insulin, a scientific breakthrough that transformed Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, from a terminal disease into a manageable condition. Today, Type 2 diabetes is 24 times more prevalent than Type 1. The rise in rates of obesity and incidence […]