Midlife Cognitive Problems Tied to Sleep Disruptions Earlier in Life
People who had fragmented sleep in their 30s and 40s were more likely to have worse cognition a decade later, longitudinal data showed. Those in the highest versus the lowest tertile of the sleep fragmentation index had over twice the odds of performing poorly on three types of cognitive tests 11 years later, said Yue […]
Menopausal Women With Obesity Endure Worse Symptoms, Less HT Relief
PHILADELPHIA — Women with obesity may experience worse menopausal symptoms and see less relief from hormone therapy (HT), according to a pilot study. When compared with women without obesity, those with a BMI of 30 or greater were significantly more likely to report menopause-related vasomotor symptoms like hot flashes and night sweats (74% vs 45%, […]
Some NSCLC Patients on ICI Therapy Fare Worse With Proton Pump Inhibitor Use
Proton pump inhibitor (PPI) use was independently associated with worse treatment outcomes in some patients with non-small cell lung cancer (NSCLC) on immune checkpoint inhibitor (ICI) therapy with pembrolizumab (Keytruda), according to a Japanese multicenter cohort study. Among patients with a PD-L1 tumor proportion score (TPS) of 50% or more, a history of PPI use […]
5 Exercises You Should Never Do If You Have Knee Issues
piranka via Getty Images Certain exercises can make your knee pain worse and even cause further damage, experts say. Knee injuries, knee pain and general wear and tear on the joints are common occurrences for many people ― and they should be considered when picking your workouts. There are many kinds of common knee injuries, […]
John Fetterman Describes Deep Depression After Dr. Oz Debate: ‘I Wasn’t Functional’
Sen. John Fetterman (D-Pa.) says his mental health took a sharp turn for the worse last year after he struggled during a nationally televised debate against his opponent in the Senate race, Mehmet Oz. The Pennsylvania politician, 53, opened up about his personal experience with depression in an interview alongside his wife, Gisele Fetterman, published […]
Post-Op Pain Control More Challenging for Cannabis Users
NEW ORLEANS — Cannabis users reported somewhat worse postoperative pain compared with people who did not use cannabis before surgery, according to a large observational study. The difference was modest, however, as cannabis users had time-weighted average pain scores after surgery that were 0.58 higher on a scale from 0 to 10 (P<0.001), and they […]
Smaller Airways Set the Stage for Worse COPD Outcomes in Women
Smaller airways in women may explain their worse respiratory outcomes in chronic obstructive pulmonary disease (COPD), a large cohort study suggested. For never-smokers and ever-smokers alike, CT imaging revealed that men had thicker airway walls than women, who also had smaller airway lumen dimensions after accounting for height and total lung capacity. “It is plausible […]
Communities with higher levels of racial prejudice have worse health outcomes: Area-level racial prejudice drives health inequities, research finds
People who live in communities with higher levels of racial prejudice have worse health outcomes, including more heart disease and mental health problems and higher overall mortality rates, according to research published by the American Psychological Association. The researchers conducted a systematic review of fourteen papers that used data gathered from Google, Twitter and other […]
COVID Makes Everything Worse in Pregnancy
Pregnant women with COVID-19 had worse outcomes across the board, especially if the mother-to-be was also co-infected with HIV, according to a study from Botswana. Adverse birth outcomes, such as premature delivery and stillbirth, were observed in 31% of women who tested positive for COVID-19 compared with 26% of women who did not (adjusted RR […]
Several Factors Contribute to GI Bleeding Mortality Risk
Patients who developed upper gastrointestinal (GI) bleeding during a hospital stay experienced worse adverse outcomes than those admitted for upper GI bleeding alone, French researchers found in a prospective study. Currently hospitalized patients (dubbed “inpatients”) with upper GI bleeding showed a significantly higher mortality rate at 6 weeks than patients hospitalized for GI bleeding alone […]