For Kids With Sickle Cell Disease Prescribed Opioids, No Patterns of Misuse Emerged
No patterns of long-term or increasing use of opioids were identified within 3 years among opioid-naive children with sickle cell disease (SCD) who were prescribed the drugs for an acute pain episode, according to a retrospective cohort study. In the cohort of 725 children, mean days’ supply of opioids over 3 years was 30, despite […]
Very Early ART Can Result in Sustained HIV Suppression in Neonates
In neonates with acquired in utero HIV infection, administration of antiretroviral therapy (ART) within 48 hours of life can lead to sustained HIV virological suppression by 2 years, a phase I/II proof-of-concept study indicated. In two cohorts who received three-drug nevirapine-based ART regimens within two days of life and maintained protocol- defined virological control criteria […]
Surgery No Help for the Kidneys in Older Folks With Primary Hyperparathyroidism
Parathyroidectomy within the first year after a primary hyperparathyroidism (PHPT) diagnosis wasn’t much help for preserving kidney function in older adults, an observational study suggested. Looking at over 43,000 patients with PHPT, there was no difference in the risk for estimated glomerular filtration rate (eGFR) decline between patients managed surgically with early parathyroidectomy compared with […]
Early DAPT Improves Outcomes for Strokes With No Other Tx Options
DALLAS — Adding tirofiban (Aggrastat) to aspirin for dual antiplatelet therapy (DAPT) within 24 hours of acute ischemic stroke improved outcomes for patients who weren’t candidates for thrombolytic or endovascular treatment, according to a phase III trial from China. The combination of the glycoprotein IIb/IIIa inhibitor with aspirin shifted modified Rankin Scale (mRS) scores in […]
Opinion | ‘It Appears All the Cylinders Are Firing Within His Brain’: What We Heard This Week
“It appears that all the cylinders are firing within his brain.” — Timothy Pritts, MD, PhD, of the University of Cincinnati Medical Center, where NFL safety Damar Hamlin was treated after he collapsed on the field during a Monday Night Football game. “All of a sudden, this guy in a pink dress came up next […]
Breakthrough Monkeypox Cases Seen Weeks After Second Jynneos Dose
Most cases of monkeypox post-vaccination occurred within 2 weeks of the first Jynneos dose, a single-center study found, but some breakthrough cases developed weeks after a second dose of the vaccine. Of 90 individuals who tested positive for monkeypox after a single dose of Jynneos at a large monkeypox testing and vaccination site, 77% of […]
Top 10 Highest Paying Healthcare Jobs
[embedded content] There are many different career options within healthcare, each with their own unique roles and responsibilities, but which ones pay you the most for your time? Although money should never be your primary motivation when choosing a career, it is still an important part of the decision-making process. Another important factor to consider, […]
Experts Predict If And When COVID Will Become A Seasonal Illness
The vast majority of respiratory viruses that spread within our population ebb and flow with the seasons. Influenza spikes in the winter months, as do infections caused by respiratory syncytial virus (RSV), adenoviruses and other coronaviruses. Earlier this year, Rochelle Walensky, the Centers for Disease Control and Prevention director, said she expects COVID to also […]
Study reveals Stonehenge landscape before the world-famous monument
Four thousand years before Stonehenge was constructed, land within the World Heritage Site was covered by open woodland, with meadow-like clearings, inhabited by grazing animals and hunter-gatherers, according to new research by the University of Southampton. Scientists exploring Blick Mead, a Mesolithic archaeological site within a chalkland spring area about a mile from the iconic […]
New method for probing the bewildering diversity of the microbiome
In recent years, researchers have begun to explore the vast assemblage of microbes on and within the human body. These include protists, archaea, fungi, viruses and vast numbers of bacteria living in symbiotic ecosystems. Known collectively as the human microbiome, these tiny entities influence an astonishing range of activities, from metabolism to behavior and play […]