Mobile alert app for missing people with dementia
Researchers are working with community leaders to develop a mobile alert app to help locate missing people with dementia. Noelannah Neubauer, a postdoctoral fellow at the University of Waterloo’s School of Public Health Sciences, said “Community ASAP” is aimed at addressing a gap in available tools when it comes to alerts for missing older adults […]
Oral Drug Active in Teens With Atopic Dermatitis
Teenagers with moderate or severe atopic dermatitis (AD) had significant improvement at 12 weeks with the investigational oral Janus kinase (JAK) inhibitor abrocitinib plus topical therapy, a placebo-controlled trial showed. Almost half of the patients had clear or almost clear skin by clinician assessment (IGA), and about 70% of patients treated with either of two […]
Tyrannosaurus rex’s jaw had sensors to make it an even more fearsome predator
Tyrannosaurus rex was not just a huge beast with a big bite, it had nerve sensors in the very tips of its jaw enabling it to better detect — and eat — its prey, a new study published in the peer-reviewed journal Historical Biology today finds. “T. rex was an even more fearsome predator than […]
How Long Is a Person Contagious With Mono?
After exposure to the virus, someone with mono can be contagious for months, even before symptoms start and after symptoms subside Infectious mononucleosis, also called mono, is a contagious disease most commonly caused by the Epstein-Barr virus (EBV). It’s unclear how long someone with mono is contagious, although they are definitely contagious while they have […]
PD-1 Inhibitor OK’d as Adjuvant Therapy for Bladder Cancer
The FDA has approved nivolumab (Opdivo) as an adjuvant therapy for patients with urothelial carcinoma (UC) who are at high risk of recurrence after undergoing radical resection, regardless of prior neoadjuvant chemotherapy, nodal involvement, or PD-L1 status, Bristol Myers Squibb announced. Nivolumab becomes the first PD-1 inhibitor in UC with an indication in the adjuvant […]
Rheumatic Events With Checkpoint Inhibitors: Tumor Type Matters
Among the factors that were associated with an increased risk for the development of rheumatic immune-related adverse events following cancer treatment with immune checkpoint inhibitors (ICIs) was the type of malignancy involved, a large case-control study found. Compared with reference lung cancer (the most common type of malignancy in this cohort), the development of a […]
Global Suicides Rise; Outgrowing ADHD; A 40-Year Soda Addiction
Over the past 30 years, global suicide deaths rose by almost 20,000, with most countries seeing the highest suicide rates in people ages 70 and older. (Injury Prevention) The FDA cleared BrainsWay’s Deep Transcranial Magnetic Stimulation (TMS) system for anxious depression, the company announced. The TMS system was already indicated for major depressive disorder, obsessive-compulsive […]
Stop Resisting the ‘Imposter’ Inside of You
The problem with feeling like an imposter is thinking there’s something wrong with it. I know this is different from any way you have thought about it, but humor me. What happens when we are offered an opportunity, but we feel like an imposter? We hide. We overwork to compensate. We look around at our […]
A Gut-Wrenching Pandemic for Patients With Functional GI Issues
Patients with irritable bowel syndrome (IBS), gastroparesis, or functional dyspepsia had more gastrointestinal symptoms during the pandemic, a retrospective single-center study found. Compared to the 6 months before the pandemic, more patients with common functional gastrointestinal and motility disorders (FGIMD) experienced symptoms during the pandemic, including nausea or vomiting (16% vs 22%, respectively), constipation (13% […]
Small protein protects pancreatic cells in model of type 1 diabetes
A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease. The small protein that first made headlines as an “exercise mimetic” increasingly appears to also have a big role in regulating the […]