Opinion | Two Women Physicians Find Empowerment Through Entrepreneurship
Joshi is a physician and entrepreneur. The life of a physician is fraught with setbacks and struggles. For women who enter medicine, it’s even more cumbersome. Nearly every woman in medicine must deal with the burden of proof — that she’s earned her title and position along the way from medical school to independent clinical […]
Helping caregivers help people with dementia eat at home
For many people with dementia and the caregivers helping them live at home, mealtime is no picnic. The home environment can pose challenges for both the patient and those providing care — confusion and functional problems linked to dementia and a lack of caregiver support for friends and family members thrust into the role, to […]
Radioligand Therapy Continues to Show Promise for Metastatic CRPC
Radioligand therapy (RLT) with actinium-225 targeting prostate-specific membrane antigen (225Ac-PSMA) had a “substantial antitumor effect” in heavily pretreated metastatic castration-resistant prostate cancer (mCRPC), a large, retrospective, multicenter study showed. Data on 488 men showed an overall survival (OS) of 15.5 months and median progression-free survival (PFS) of 7.9 months. A third of the patients had […]
FDA OKs First Cellular Therapy for Melanoma
The FDA approved the cellular therapy lifileucel (Amtagvi) for the treatment of patients with previously treated unresectable or metastatic melanoma, the agency announced Friday. Lifileucel, a cellular therapy with tumor-infiltrating lymphocytes (TILs), was approved through the accelerated approval pathway, and is the first FDA-approved tumor-derived T-cell immunotherapy, the FDA noted. “Unresectable or metastatic melanoma is […]
How parents can help prevent the development of ADHD symptoms
Parents of young children with an excitable or exuberant temperament could adapt their parenting style to help moderate their child’s potential development of Attention Deficit/Hyperactivity Disorder (ADHD), according to a new study co-authored by a University of Waterloo researcher. Developmental psychologists know that temperament, parenting, and the brain’s executive functions are interconnected factors in developing […]
More Data Support Olaparib-Abiraterone in BRCA-Mutant Prostate Cancer
Combining olaparib (Lynparza) with abiraterone acetate (Zytiga) as first-line therapy for biomarker-selected patients with metastatic castration-resistant prostate cancer significantly improved progression-free survival (PFS) versus either agent alone, according to findings from a small phase II trial presented at this year’s Genitourinary Cancers Symposium. In this exclusive MedPage Today video, Daniel Geynisman, MD, of Fox Chase […]
Another Study Backs Treatment for Preclinical Rheumatoid Arthritis
Inflammatory markers were reduced in patients with persistent joint pain and other markers for incipient rheumatoid arthritis (RA), as was progression to formal RA diagnosis, after a 6-month course of abatacept (Orencia) in a placebo-controlled trial. While 35% of controls were diagnosed with RA while on treatment in the trial, called ARIAA, only 8% of […]
VA Can Be a Leader in Healthcare AI, Lawmakers Say
The Department of Veterans Affairs (VA) must balance innovation with careful implementation of emerging artificial intelligence (AI) technology, lawmakers and witnesses said during a House hearing on Thursday. “The VA is not an island. AI efforts within the federal government are proceeding in parallel, while private industry is significantly ahead of the public sector. Even […]
Oldest Patient ‘Cured’ of HIV Still in Remission 5 Years After Transplant for AML
A 68-year-old man with HIV-1 who underwent hematopoietic cell transplant (HCT) for acute myelogenous leukemia 5 years ago has been free of HIV infection for 35 months after stopping antiretroviral treatment (ART), according to a case report. The patient received an HCT from a donor with the rare delta-32 mutation, which causes a CCR5 deletion […]
Female Reproductive Factors Linked to COPD Risk
Female reproductive factors were associated with risk of chronic obstructive pulmonary disease (COPD), including age at menarche, number of children, miscarriage, stillbirth, and age at natural menopause, according to an analysis of three cohorts. Among nearly 300,000 women, a U-shaped association was observed between age at menarche and COPD (≤11 vs 13 years: HR 1.17, […]