Breast Cancer Survivors Who Work Out See Heart Benefits
Physical activity among long-term breast cancer survivors was associated with better global longitudinal strain (GLS), though not left ventricular ejection fraction (LVEF), data from a cohort study found. Compared with inactive survivors, moderately active breast cancer survivors had a 35% lower risk of abnormal GLS (relative risk [RR] 0.65, 95% CI 0.45-0.94) while active survivors […]
Genotype Tied to Azathioprine Discontinuation for Toxicity
Patients with inflammatory conditions who have the CC genotype were at greater risk both for discontinuing the use of azathioprine (Imuran) due to hematopoietic toxicity and for needing to switch to lower doses, a retrospective cohort study found. In a competing-risk analysis involving over 1,400 such patients starting on azathioprine, those who carried the CC […]
A rare discovery of long-term memory in wild frog-eating bats: 4 years after first exposure, bats remember a ringtone’s link to food
Frog-eating bats trained by researchers to associate a phone ringtone with a tasty treat were able to remember what they learned for up to four years in the wild, new research has found. The study acquainted 49 bats with a series of ringtones that attracted their attention, and trained them to associate flying toward just […]
Can You Be Bipolar With Dementia?
You can have bipolar disorder with dementia. Learn about how mood disorders can affect cognitive function Studies have shown that people who have bipolar disorder are at an increased risk of dementia. Because bipolar disorders are bound to alter brain structure and chemistry over time, there may be gradual damage to brain cells that can lead […]
MRI-Guided HIFU Effective in Intermediate-Risk Prostate Cancer
MRI-guided high-intensity focused ultrasound (HIFU) is effective in patients with intermediate-risk prostate cancer, researchers reported. According to the team’s multicenter, single-arm, phase IIb study of 101 patients who received the treatment, 96% had no evidence of grade group 2 or higher prostate cancer on 6-month MRI-targeted and systematic biopsy in the treated area of the […]
Healthier Lifestyle Maintained After Bariatric Surgery
Bariatric surgery patients tended to maintain healthier lifestyle habits compared with peers who were eligible but had not received this treatment, according to data from the National Health and Nutrition Examination Survey (NHANES). People approximately 7 years out of bariatric surgery reported more moderate-to-vigorous physical activity (MVPA) than those who were eligible but did not […]
FDA Advisers Reject Nuplazid for Alzheimer’s Disease Psychosis
An FDA advisory panel rejected pimavanserin (Nuplazid) for the treatment of hallucinations and delusions in patients with Alzheimer’s disease psychosis on Friday. In a vote of 9-3, the Psychopharmacologic Drugs Advisory Committee decided against recommending the drug for approval for these patients, citing a slew of shortcomings in supporting trial data. This could have been […]
Xtandi During AS Reduced Progression Risk in Early Prostate Cancer
Patients with low- or intermediate-risk localized prostate cancer who received enzalutamide (Xtandi) monotherapy saw a reduced risk of cancer progression, according to a randomized phase II trial. Among 227 patients on active surveillance (AS), treatment with enzalutamide reduced the risk of pathological or therapeutic prostate cancer progression by 46% compared with AS alone (HR 0.54, […]
Early Anal Lesion Treatment Cuts Cancer Risk in People With HIV
Treating precancerous anal lesions in people with HIV reduced their risk of developing anal cancer by more than half compared with active monitoring, according to results from the ANCHOR study. In the randomized phase III trial of more than 4,500 individuals with anal high-grade squamous intraepithelial lesions (HSIL), nine of those assigned to treatment with […]
There’s A Name For The Heavy Feelings You’re Carrying At Work Right Now
If you feel like you are at the breaking point right now at your job, you are not alone. Americans are coping with what is known as “cascading collective trauma,” as termed by Roxane Cohen Silver, a University of California at Irvine psychologist who has researched trauma for decades. In an article published in the […]