Increasing BMI in Kids Tied to 100% Fruit Juice Consumption
Daily consumption of 100% fruit juice was associated with a small increase in body mass index (BMI) in children, while an association between consumption and weight gain among adults appeared mixed, a systematic review and meta-analysis found. In prospective cohort studies involving kids, each 8-oz serving of 100% fruit juice was associated with a 0.03 […]
This Worth-Every-Penny Electric Toothbrush Is Almost 40% Off
Amazon Available in four colors, the Philips Sonicare toothbrush also comes with a charging travel case. HuffPost and its publishing partners may receive a commission from some purchases made via links on this page. Every item is independently curated by the HuffPost Shopping team. Prices and availability are subject to change. There’s nothing quite as […]
No Laughing Matter: Nitrous Oxide for Transrectal Prostate Biopsy
Patient-adjusted nitrous oxide (N2O), commonly called laughing gas, did not reduce anxiety associated with transrectal prostate biopsy but significantly reduced pain as compared with standard anesthesia, a small randomized study showed. Scores on a standardized anxiety questionnaire, the primary endpoint, did not differ significantly between patients randomized to N2O or standard care. However, patents in […]
EGFR Inhibitors for Lung Cancer Tied to Increased Keratitis Risk
Patients with lung cancer treated with epidermal growth factor receptor (EGFR) inhibitors may have an increased risk of new-onset keratitis, a U.S. population-based cohort study showed. Over a 20-year period, 1.12% of patients who were treated with EGFR inhibitors developed new-onset keratitis compared with 0.74% of those who did not take these drugs (HR 1.520, […]
Linezolid ‘Not Recommended’ to Treat Early Syphilis
Linezolid failed to meet noninferiority criteria when compared with standard benzathine penicillin G (BPG) in the treatment of early syphilis, according to findings of the randomized, controlled Trep-AB Study of cisgender men. Only 70% of trial participants with early syphilis who were treated with linezolid were cured, compared with 100% of participants treated with penicillin, […]
More Evidence Linking ADT for Prostate Cancer to Adverse Neurocognitive Effects
Men treated with androgen deprivation therapy (ADT) for prostate cancer had a significantly higher risk of dementia and other neurocognitive disorders, according to a meta-analysis of more than 2.5 million patients. The magnitude of excess risk ranged from 20% for dementia to 66% for depression. The risk of Alzheimer’s disease, vascular dementia, and Parkinson’s disease […]
Early Bird? Night Owl? It May Matter for Eating Disorder Risk
People with anorexia nervosa may be more likely to be early risers, a genetic association study suggested. Looking at nearly 17,000 cases with this eating disorder, genetic liability for anorexia nervosa was associated with a more morning chronotype — or a preference for the morning (β=0.039, 95% CI 0.006-0.072, P=0.02), Hassan Dashti, PhD, RD, of […]
Opening Blood-Brain Barrier to Deliver Alzheimer’s Drug Shows Promise
Aducanumab (Aduhelm) infusions combined with focused ultrasound led to lower cerebral amyloid-beta levels in Alzheimer’s disease, a proof-of-concept trial showed. The investigational treatment involved creating an opening in the blood-brain barrier with MRI-guided focused ultrasound to boost drug delivery. In each of three participants who received aducanumab infusions, amyloid reduction was greater in brain regions […]
Paramagnetic Seeds: An Effective Option for Breast Lesion Localization
Paramagnetic seeds along with superparamagnetic iron oxide (SPIO) was an effective combination for nonpalpable breast lesion localization and sentinel lymph node detection (SLND), data from the MAGTOTAL trial in Sweden showed. The totally magnetic technique was equivalent to the use of guidewire and SPIO regarding re-excision frequency at 2.84% versus 2.87%, for a difference of […]
Mortality Reaches 20% for Hospitalized Patients With High-Risk Pulmonary Embolism
Mortality rates were high among patients with high-risk pulmonary embolism (PE), with the worst outcomes in those with hemodynamic collapse, according to a retrospective analysis of the Pulmonary Embolism Response Team (PERT) Consortium Registry. In nearly 5,800 patients, in-hospital mortality occurred over five times more frequently among those with high-risk PE compared with those with […]