5 Foods That Aren’t Doing Your Cholesterol Any Favors
krisanapong detraphiphat via Getty Images Full-fat dairy is, generally, not advisable for folks with high cholesterol. Throughout the United States, high cholesterol is a common issue. According to the Centers for Disease Control and Prevention, two in five American adults deal with the condition, putting them at increased risk of stroke and heart attack. Cholesterol […]
Peripheral IV Access for Chemo Better Than Central Lines in Testicular Cancer?
Patients with testicular cancer had fewer venous access-related complications and overall thrombotic events when first-line chemotherapy was delivered via peripheral intravenous access compared with central venous access devices (CVADs), a retrospective study suggested. Among 154 patients, those in the CVAD group compared with the peripheral IV group experienced more venous access-related complications (52.2% vs 24.2%) […]
One Class of Antidiabetic Linked With Lower Kidney Stone Risk
One class of glucose-lowering agent may help lower the risk of kidney stones in adults with type 2 diabetes, a cohort study suggested. Adults who newly started on an SGLT2 inhibitor had a 31% lower risk of nephrolithiasis compared with those starting on a GLP-1 receptor agonist (HR 0.69, 95% CI 0.67-0.72), found Julie M. […]
Study urges people to think twice before going on a diet
A new qualitative study highlights the negative interpersonal and psychological consequences associated with “yo-yo dieting,” also known as weight cycling. The work underscores how toxic yo-yo dieting can be and how difficult it can be for people to break the cycle. “Yo-yo dieting — unintentionally gaining weight and dieting to lose weight only to gain […]
How obesity dismantles our mitochondria
The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors like diet and exercise play a role in the development and progression of obesity, scientists have come to understand that obesity is also associated with intrinsic metabolic abnormalities. Now, researchers from University of California San Diego […]
Switching Twice With Infliximab Biosimilars Not Linked With IBD Flare Risk
LAS VEGAS — Biosimilar switching was not tied to flare in patients with inflammatory bowel disease (IBD), according to a retrospective cohort study. Patients who switched from infliximab (Remicade) to an infliximab biosimilar, and then switched again to a different biosimilar or back to infliximab, were no more or less likely to experience a disease […]
A Win and A Loss for Adjuvant ICIs in Clear Cell Renal Cell Carcinoma
SAN FRANCISCO — The use of adjuvant pembrolizumab (Keytruda) boosted overall survival (OS) in post-surgical patients with clear cell renal cell carcinoma (RCC) at risk for recurrence, according to KEYNOTE-564 findings. Patients treated with the immune checkpoint inhibitor (ICI) had a 38% reduced risk of death compared to patients on placebo, reported Tony Choueiri, MD, […]
Effective Treatments Identified for Pediatric Complication of COVID
PHOENIX — First-line treatment with methylprednisolone and second-line treatment with tocilizumab (Actemra) shortened hospital stays for children with pediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS; also referred to as multisystem inflammatory syndrome in children [MIS-C]), according to results of a two-stage clinical trial from the RECOVERY collaborative group. In 214 children randomly assigned […]
Cabozantinib Plus Atezolizumab Delays Progression in mCRPC
SAN FRANCISCO — In patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease progressed on a novel hormonal therapy, the combination of cabozantinib (Cabometyx) plus atezolizumab (Tecentriq) improved radiographic progression-free survival (rPFS) versus a switch to a second hormonal agent, a phase III trial showed. The so-called CONTACT-02 study included patients with extrapelvic nodal or […]
Has ‘Little Treat’ Culture Gone Too Far? Therapists Have Thoughts.
LOADINGERROR LOADING You may not know it had a name, but you’re likely familiar with the concept of “little treat” culture, as it’s come to be known on TikTok and elsewhere on the internet. It’s the act of indulging in small and inexpensive pleasures, either as a reward for doing a task or sometimes just […]