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Opinion | The Pandemic Potential of U.S. Animal Markets

Linder is an expert in animal policy and law. COVID hit the U.S. while my partner and I were back home at a wedding in Kansas. At the time, there were a handful of cases on the coasts, but concerns about the new virus were drowned out by the busy reception full of hugs and […]

Some Health Workers See Double the Risk for Fatal Drug Overdoses

Certain healthcare workers including registered nurses (RNs) were at increased risk for fatal drug overdoses, a longitudinal study from 2008 to 2019 found. After adjustment for various factors, the risk for overdose death was more than twofold higher for RNs (HR 2.22, 95% CI 1.57-3.13) and social or behavioral health workers (HR 2.55, 95% CI […]

Breast Cancer Overdiagnosis Risk May Be Substantial for Older Women

Older women screened for breast cancer were at a considerable risk of being overdiagnosed, according to a large retrospective cohort study. Researchers found that an estimated 31% of breast cancers among screened women from the ages of 70 and 74 were potentially overdiagnosed, reported Ilana Richman, MD, MHS, of the Yale School of Medicine in […]

Sleep Quality Linked With Cognition Across Five Cohorts

AMSTERDAM — Better sleep consolidation and the absence of sleep apnea were associated with better global cognition over 5 years, a pooled analysis of sleep studies in nearly 6,000 adults showed. Across five cohorts, higher sleep maintenance efficiency (pooled β per 1% increase 0.08, P<0.01) and lower wake after sleep onset (pooled β per 1-min […]

Dementia Tied to Fluctuations in Blood Lipids Over Time

Fluctuations in total cholesterol and triglyceride levels in people 60 and older were tied to a higher risk of incident dementia, including Alzheimer’s disease, a longitudinal study showed. Over a median follow-up of 12.9 years, participants in the highest quintile of total cholesterol variability versus the lowest quintile had a 19% increased risk of incident […]

New Data on BCMA-Directed Bispecifics in Multiple Myeloma

Promising data on new B-cell maturation antigen (BCMA)-directed bispecific antibodies were presented at the American Society of Clinical Oncology (ASCO) annual meeting. These included results on two investigational products: the phase II LINKER-MM1 study, which showed that linvoseltamab elicited an objective response rate of 71% at the recommended dose of 200 mg for patients with […]

Protocol Optimizing Meds for T2D and CVD Pushed Beyond Cardiology Alone

SAN DIEGO — Cardiovascular medications were better optimized for patients with type 2 diabetes (T2D) and atherosclerotic cardiovascular disease (ASCVD) following a multifaceted intervention involving clinician and patient education, the cluster-randomized COORDINATE-Diabetes trial found. At cardiology clinics following the intervention protocol, prescriptions increased several-fold compared with usual care (37.9% vs 14.5%; adjusted OR 4.28, 95% […]

Across Borders, Worse COVID Outcomes Seen in Polluted Areas

During the pandemic, people exposed to more air pollution were at greater risk of COVID-19 infection, hospitalization, and death, a nationwide study from Denmark showed. Based on the country’s COVID-19 surveillance system covering over 3.7 million residents, there were significant associations between local levels of inhalable particulate matter (PM2.5) and nitrogen dioxide (NO2) and incident […]

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