RSV Vaccine Maintains Efficacy Across Two Seasons in Seniors
BOSTON — Efficacy of GSK’s respiratory syncytial virus (RSV) vaccine held strong through two RSV seasons in adults 60 and over, according to new results from the company’s pivotal trial. With a single dose, efficacy of the RSV perfusion F protein vaccine (Arexvy) against RSV-related lower respiratory tract disease declined from 82.6% during the first […]
How Bad Will This Respiratory Virus Season Be? CDC Weighs In.
The CDC predicted that this year’s fall and winter virus season will look a lot like last year’s. “The bottom line here is we’re likely to have a similar number of total hospitalizations as we had last year,” Dylan George, PhD, director of the CDC’s Center for Forecasting and Outbreak Analytics, told reporters during a […]
CDC Advisors Endorse Maternal RSV Vax to Protect Newborns
The CDC’s advisors on Friday recommended a maternal respiratory syncytial virus (RSV) vaccine to protect infants from serious infections. By an 11-1 vote, the Advisory Committee on Immunization Practices (ACIP) recommended that pregnant women receive a single dose of Pfizer’s prefusion F protein (RSVpreF) vaccine (Abrysvo) at 32 to 36 weeks’ gestation to prevent lower […]
Increased West Nile Virus Cases, Including Death, Confirmed – Wyoming Department of Health
Increased West Nile Virus Cases, Including Death, Confirmed September 11, 2023 As Wyoming experiences more West Nile virus (WNV) activity this season than over the past decade or so, the Wyoming Department of Health (WDH) is emphasizing mosquito bite prevention. There have been 20 cases reported, including a death in an older adult Fremont County […]
Increased West Nile Virus Cases, Including Death, Confirmed – Wyoming Department of Health
Increased West Nile Virus Cases, Including Death, Confirmed September 11, 2023 As Wyoming experiences more West Nile virus (WNV) activity this season than over the past decade or so, the Wyoming Department of Health (WDH) is emphasizing mosquito bite prevention. There have been 20 cases reported, including a death in an older adult Fremont County […]
What to Know About New Tools to Fight RSV
The tide may be turning on respiratory syncytial virus (RSV), a seasonal scourge that’s responsible for a substantial number of hospitalizations and deaths among older people and young children each year. In the span of just a few months, the FDA has approved two vaccines and a monoclonal antibody for use in specific populations with […]
COVID-19 Impaired Fertility Treatments
Couples infected with the COVID-19 virus while receiving assisted reproductive technology treatment had lower quality embryo and blastocyst rates when compared to non-infected couples, a retrospective cohort study in China showed. In nearly 600 couples who underwent in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment at a reproductive center, SARS-CoV-2–positive couples had significantly […]
Second RSV Vaccine Lands Approval for Older Adults
The FDA has approved a second respiratory syncytial virus (RSV) vaccine for preventing lower respiratory infections in adults 60 and over, Pfizer announced on Wednesday. Approval of the unadjuvanted, bivalent RSV prefusion F protein vaccine (Abrysvo) follows an endorsement in March from FDA’s Vaccines and Related Biological Products Advisory Committee (VRBPAC). Advisors voted 7-4 in […]
Safety Data on Maternal RSV Vaccine ‘Favorable,’ FDA Staff Says
A maternal respiratory syncytial virus (RSV) vaccine candidate prevents infections in infants and comes with “generally favorable” safety data, said FDA staff in briefing documents released ahead of an advisory committee meeting this week, but the reviewers “noted potential uncertainty based on the numerical imbalance in premature deliveries.” On Thursday, members of the Vaccines and […]
‘Fantastic,’ ‘Terrific’ Results With Oncolytic Virus Combo for Bladder Cancer
CHICAGO — An oncolytic virus therapy combined with pembrolizumab (Keytruda) produced complete responses (CRs) in 85% of patients with bacillus Calmette-Guérin (BCG)-unresponsive non-muscle-invasive bladder cancer (NMIBC), a small phase II trial showed. The results showed CRs in 29 of 34 patients with detectable carcinoma in situ (CIS) treated with cretostimogene grenadenorepvec (CG0070) and the PD-1 […]