High PSMA Predictive of Good Response to Radioisotope Therapy in Prostate Cancer
Uptake of a transmembrane protein, which is expressed by virtually all prostate cancers, on imaging could be a viable predictive biomarker of patient response to isotope-based therapy, according to data from the phase II TheraP trial. High baseline prostate-specific membrane antigen (PSMA) uptake on PET was predictive of a favorable response to treatment with lutetium-177 […]
Breast Cancer Control Similar With Intermittent, Continuous Endocrine Therapy
Intermittent or continuous extended adjuvant endocrine therapy led to virtually identical long-term survival in hormone receptor (HR)-positive breast cancer, according to an updated analysis of a randomized trial. Disease-free survival (DFS) at 7 years was 81.4% with intermittent extended letrozole and 81.5% with continuous treatment. The results mirrored previously reported 5-year DFS, which also did […]