Zika Virus: Vaccine, Symptoms, Contagious, Treatment & Risks During Pregnant
Things to know about Zika virus Picture of an Aedes aegypti mosquito, a vector that transmits the Zika virus; Photo by James Gathany Zika virus is a virus related to dengue, West Nile, and other viruses. Zika virus may play a role in developing congenital microcephaly (small head and brain) in the fetus of infected […]
Liver Toxicity in Gene Therapy Trials Could Merit Stricter Entry Criteria
An FDA advisory committee offered up lower vector doses, stricter exclusion criteria, and long-term animal studies to grapple with liver toxicities associated with adeno-associated virus (AAV) vector-based gene therapies. During the second of four sessions on AAV safety, the Cellular, Tissue, and Gene Therapies Advisory Committee (CTGTAC) weighed evidence of hepatotoxicity — ranging from liver […]