Reassuring Registry Data on Going Into TAVR Sans Symptoms
Transcatheter aortic valve replacement (TAVR) got some preliminary affirmation for asymptomatic or minimally symptomatic severe aortic stenosis in a retrospective registry study. Of participants who got elective TAVR, the one in five who had minimal symptoms before the procedure tended to have good outcomes that compared favorably against the majority of more symptomatic peers: Fewer […]
PPI Still Common With Self-Expanding TAVR
Need for a pacemaker after transfemoral transcatheter aortic valve replacement (TAVR) with a self-expanding device was both common and impactful for mortality, but the risk appeared to be modifiable, international registry data showed. Of patients treated with an Acurate neo/neo2 (approved outside the U.S.) or Evolut PRO/PRO+ valve, 11.3% needed new permanent pacemaker implantation (PPI) […]
Bicuspid Aortic Valves and Aortopathy Cluster Among Close Relatives
Diagnoses of bicuspid aortic valve (BAV), thoracic aortic aneurysm, and thoracic aortic dissection appeared to run in families extending beyond first-degree relatives, according to the largest pedigree-based study on the subject to date. Among probands with BAV and aortopathy in the Utah Population Database, first-degree relatives were several times more likely to share a concordant […]
Real-World Data Affirms Next-Gen TAVR Device Advantage
PHOENIX — The newer generation Evolut transcatheter aortic valve replacement (TAVR) device improved on procedural and possibly safety characteristics, the TVT registry showed. The Evolut FX device reduced need for device repositioning and cut procedure time, without a change in valve hemodynamics, at 30 days compared with the Evolut Pro+ device, reported Wah Wah Htun, […]
Transapical Transcatheter Mitral Valve Replacement Trial Raises Questions
PHOENIX — Global experience with the novel Intrepid transapical transcatheter mitral valve replacement (TMVR) device through 2 years showed high risks of mortality and complications, raising concerns that might not be alleviated by the planned shift to a transfemoral approach. In the analysis pooling data from a pilot study and the APOLLO trial, the high-risk […]
Skipping Antiplatelets Altogether Not Such a Bad Idea for Select TAVR Patients
Following transcatheter aortic valve replacement (TAVR), the optimal antithrombotic regimen for some people may be no antithrombotics at all, according to provocative registry data from Japan. Compared with the single antiplatelet (SAPT) or dual antiplatelet (DAPT) approaches for TAVR patients without any other indications for antiplatelet or anticoagulation therapy, the non-antithrombotic strategy was not associated […]
Is TAVR in Small Aortic Annuli Better With Self-Expanding Valves?
BOSTON — Transcatheter aortic valve replacement (TAVR) in patients with small aortic annuli had better hemodynamic results with a self-expandable than a balloon-expandable valve, with suggestion of better clinical outcomes too, in the France-TAVI registry. Mean gradient was significantly lower with self-expanding Medtronic CoreValve Evolut Pro or R devices at the end of the procedure […]
Mitral Valve Repair Devices Go Head-to-Head, and the Top Spot Belongs to…
BOSTON — The Pascal device for edge-to-edge mitral valve repair was as safe and effective as the MitraClip device, the pivotal CLASP IID trial showed. In a pre-specified interim analysis of the first 180 patients enrolled, Pascal was non-inferior for the primary effectiveness endpoint of proportion of patients with mitral regurgitation no worse than 2+ […]
Timing of heart surgery crucial, research shows
Valve replacement heart surgery should be performed earlier than conventionally thought for people with aortic stenosis — according to new research from the University of East Anglia. The condition is one of the most common and serious valve disease problems, caused by a narrowing of the aortic valve opening. Once patients develop symptoms such as […]
Researchers find benefits and drawbacks to two-step surgical approach for ‘leaky heart valves’: Study finds better short-term outcomes, but increased need for a pacemaker
Patients with mitral and tricuspid valve regurgitation, a condition sometimes called “leaky heart valves,” appeared to do better after two years if they had a tricuspid valve repair at the time of mitral valve surgery, according to a study supported by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes […]