Shorter Antibiotic Course Noninferior for UTI Recurrence in Kids
Five days of oral antibiotic treatment for febrile urinary tract infections (UTIs) in kids was noninferior to the standard 10-day course, the randomized controlled STOP trial showed. The recurrence rate of all UTIs — febrile and non-febrile — within 30 days of treatment with oral amoxicillin-clavulanate acid was 2.8% in the short-term group compared with […]
Recurrent UTIs linked to gut microbiome, chronic inflammation: Antibiotics may increase risk of further UTIs by disrupting microbiome
One of the greatest frustrations regarding urinary tract infections (UTIs) is that they so often recur. UTIs are caused by bacteria in the urinary tract and characterized by frequent and painful urination. A round of antibiotics usually clears up the symptoms, but the relief is often temporary: A quarter of women go on to develop […]
Can Education Tackle Poor Antibiotic Prescribing in Nursing Homes?
An educational intervention to cut inappropriate antibiotic use for suspected urinary tract infections (UTIs) and lower respiratory tract infections among nursing home residents with advanced dementia had a limited impact in a cluster randomized trial. The multicomponent TRAIN-AD intervention reduced such prescribing by 33% per person-year compared with usual care (adjusted marginal rate difference −0.27, […]