Making plant-based meat alternatives more palatable
One of the biggest obstacles to the uptake of plant-based alternatives to meat is their very dry and astringent feel when they are eaten. Scientists, led by Professor Anwesha Sarkar at the University of Leeds, are revolutionising the sensation of plant proteins, transforming them from a substance that can be experienced as gloopy and dry […]
High PSMA Predictive of Good Response to Radioisotope Therapy in Prostate Cancer
Uptake of a transmembrane protein, which is expressed by virtually all prostate cancers, on imaging could be a viable predictive biomarker of patient response to isotope-based therapy, according to data from the phase II TheraP trial. High baseline prostate-specific membrane antigen (PSMA) uptake on PET was predictive of a favorable response to treatment with lutetium-177 […]
Better Outcomes Tied to More HCV Treatment for People Who Inject Drugs
A greater uptake in hepatitis C virus (HCV) treatment for people who inject drugs (PWID) at a community center led to decreases in liver disease and mortality, a longitudinal cohort study found. Among 1,323 PWID with chronic HCV at a Baltimore community-based center, the number of those with HCV RNA declined from 100% in 2006 […]
Sex Disparity Mars Rollout of Embattled HIV Treatment in Poorer Countries
In low- and middle-income countries, dolutegravir (Tivicay) uptake in women still trailed that in men months after a safety reaffirmation from the World Health Organization (WHO), a large study showed. By March 2020, cumulative incidence of uptake of the antiretroviral by women ages 16-49 was 29.4% across 11 countries, compared with 57.7% in men of […]
Surveillance for Prostate Cancer Is on the Rise — Do Men Stick It Out?
While the uptake of active surveillance (AS) for low-risk prostate cancer has increased over time, about half of patients eventually discontinue this strategy, according to an observational Canadian population-based study. The use of AS increased from 38% in 2008 to 69% in 2014; however, over this study period, 50.8% of patients discontinued AS and proceeded […]