Lorundrostat Stands a Chance Against Obesity-Related Hypertension
Among selected people with uncontrolled hypertension, blood pressure (BP) could be successfully reduced with a highly selective aldosterone synthase inhibitor, a phase II dose-finding trial found. In hypertensive patients with suppressed renin — theoretically the group most likely to benefit from reining in aldosterone production — reductions of automated office systolic BP reached up to […]
Medtronic’s Renal Denervation System for Hypertension Splits FDA Panel
A radiofrequency-based renal denervation system for uncontrolled hypertension got a cool reception from FDA advisors who nevertheless left the door open for regulatory approval. On Wednesday, the FDA’s Circulatory System Devices Panel voted 6-7 (with one abstention) that the benefits of the Symplicity Spyral multi-electrode catheter system do not outweigh its risks when used to […]
Intermittently Scanned CGM Reduced HbA1c in Type 1 Diabetes
Adults with uncontrolled type 1 diabetes saw a benefit when using intermittently scanned continuous glucose monitoring (CGM), the randomized FLASH-UK Trial showed. Compared with traditional fingerstick testing, use of a intermittently scanned CGM, which offers optional alarms for high and low blood glucose levels set by the user, reduced HbA1c levels, with an adjusted mean […]
Encephalitis Symptoms, Treatment, Diagnosis & Definition
Encephalitis Symptoms & Signs Seizures A seizure is the uncontrolled electrical activity in the brain, which may produce a physical convulsion, minor physical signs, thought disturbances, or a combination of symptoms. The type of symptoms and seizures depend on where the abnormal electrical activity takes place in the brain, what its cause is, […]