Dual Therapy Holds Its Own in Treatment-Naive HIV
MONTREAL — A two-drug combination using a generic formulation of the protease inhibitor darunavir/ritonavir plus lamivudine appeared to control HIV as well as the same combination with added tenofovir, according to results of the phase IV ANDES trial reported here. In the intention-to-treat analysis, 91% patients on the dual therapy achieved undetectable viral loads using […]
Two Drugs Better Than One for ‘Rescue’ Asthma Therapy
SAN FRANCISCO — Phase III results look very good for a two-drug combination inhaler in helping asthma patients regain symptom control when maintenance medications weren’t doing the job. In the MANDALA trial, patients using the investigational product PT027, which combines 90 μg of albuterol with 80 μg of budesonide, were significantly less likely to experience […]