New Report Reveals These Common Products May Cause Uterine Fibroids
Approximately 80% of reproductive-aged women develop uterine fibroids —non-cancerous tumors that grow in the uterus — yet it’s often unclear what causes them. Scientists have long suspected that genetics play a role, as do hormones, diet and major life stressors. New research from scientists at Northwestern University suggests that chemicals we’re exposed to in everyday […]
New Report Reveals These Common Products May Cause Uterine Fibroids
Approximately 80% of reproductive-aged women develop uterine fibroids —non-cancerous tumors that grow in the uterus — yet it’s often unclear what causes them. Scientists have long suspected that genetics play a role, as do hormones, diet and major life stressors. New research from scientists at Northwestern University suggests that chemicals we’re exposed to in everyday […]
‘Potential New Standard’ for Progressing Desmoid Tumors
PARIS — Progression-free survival (PFS) was significantly prolonged in patients with progressing desmoid tumors treated with an investigational gamma secretase inhibitor in a phase III trial. In the international DeFi study of more than 140 patients, risk for disease progression or death was reduced by 71% in the group randomized to nirogacestat, with a median […]
Colorectal cancer tumors both helped and hindered by T cells
Colorectal tumors are swarming with white blood cells, but whether these cells help or hinder the cancer is hotly debated. While some studies have shown that white blood cells heroically restrict tumor growth and combat colorectal cancer, equally compelling evidence casts the white blood cells as malignant co-conspirators — bolstering the tumor and helping it […]
Study identifies receptor that could alleviate need for chemo, radiation pre-T cell therapy
Before a patient can undergo T cell therapy designed to target cancerous tumors, the patient’s entire immune system must be destroyed with chemotherapy or radiation. The toxic side effects are well known, including nausea, extreme fatigue and hair loss. Now a research team, led by UCLA’s Anusha Kalbasi, MD, in collaboration with scientists from Stanford […]
Scientists develop and monitor two approaches to fix blood vessel abnormalities that make tumors difficult to treat: Combining the approaches may be a powerful anti-cancer strategy
Tumors send out signals that impair normal blood flow, which makes them hard to treat with every type of cancer treatment, including radiation and chemo-, targeted and immunotherapy. Impaired blood supply creates an environment low in oxygen levels — hypoxia — that causes the tumors to take on aggressive characteristics and become immuno-suppressed. To address […]
Drug mimics beneficial effects of fasting in mice: Blocking arginine metabolism leads to improved metabolic health, weight loss
An investigational cancer drug that starves tumors of their energy supply also shows evidence of improving whole body metabolism, leading to improved weight control, according to a new study in mice from researchers at Washington University School of Medicine in St. Louis. The findings are published in the journal Cell Reports Medicine. In a group […]
How moles change into melanoma
Moles and melanomas are both skin tumors that come from the same cell called melanocytes. The difference is that moles are usually harmless, while melanomas are cancerous and often deadly without treatment. In a study published today in eLife Magazine, Robert Judson-Torres, PhD, Huntsman Cancer Institute (HCI) researcher and University of Utah (U of U) […]
Varying immune cell levels in canine brain tumors could provide therapeutic targets
A new study reveals that high-grade gliomas, or brain tumors, in dogs contained more immune cells associated with suppressing immune response than low-grade gliomas. The work, which is the most extensive examination of immune cell infiltration in canine glioma to date, adds to the body of evidence that these brain tumors might recruit cells that […]
Varying immune cell levels in canine brain tumors could provide therapeutic targets
A new study reveals that high-grade gliomas, or brain tumors, in dogs contained more immune cells associated with suppressing immune response than low-grade gliomas. The work, which is the most extensive examination of immune cell infiltration in canine glioma to date, adds to the body of evidence that these brain tumors might recruit cells that […]