New Tuberculosis Framework May Improve Research, Clinical Care
A new framework may better characterize the early stages of tuberculosis (TB) and improve research and clinical care, an international team of researchers said. Turning against the current “active” or “latent” classification of TB, the International Consensus for Early TB (ICE-TB) group released a five-state system that distinguishes disease from infection, clinical versus subclinical states, […]
Common antibiotic found useful in accelerating recovery in tuberculosis patients
Globally, an estimated 10 million people develop tuberculosis (TB) each year and the disease remains a leading cause of death from a single infectious agent. Standard short-course anti-TB treatment still requires a regimen of at least six months of antimicrobial drugs, and drug-resistant TB is an increasing public health threat. Even after the traces of […]
Most People With TB Report No Persistent Cough
A significant proportion of people in the community with pulmonary tuberculosis (TB) have subclinical disease, according to a meta-analysis involving survey studies across Africa and Asia. In adjusted analyses, 82.8% (95% CI 78.6-86.6) of participants with TB reported no persistent cough and 62.5% (95% CI 56.6-68.7) reported no cough at all, according to Frank Cobelens, […]
TB Outbreak May Be Linked to Bone Repair Product
Latest Infectious Disease News FRIDAY, June 18, 2021 (HealthDay News) — A tuberculosis outbreak that may be linked to a product used to repair bones is being investigated by U.S. health officials. More than 100 patients may have been infected after having spinal surgery or fracture repairs with a bone product contaminated with […]
CDC Details Multidrug-Resistant TB Outbreak in an Unlikely Spot
An outbreak of multidrug-resistant tuberculosis (TB) developed in Kansas in November 2021, and included multiple children who were born in the U.S. and became infected in the state, CDC researchers reported. The outbreak involved 13 people across four households in Kansas City and spanned 1 year. While a majority of the seven adults identified were […]
Shorter TB Regimen Misses the Mark
Shorter high-dose rifampicin regimens proved safe for treating pulmonary tuberculosis (TB), but failed to demonstrate noninferiority compared with the standard 6-month regimen, a phase III trial found. For the primary efficacy outcome, an absolute 6.3% more adults receiving a 4-month regimen that included the highest dose of rifampicin had an unfavorable outcome at 12 to […]
Nothing Lasts Forever, Including Infant BCG Vaccine Protection
Infants who received BCG [bacille Calmette-Guérin] vaccination at birth had protection against tuberculosis into early childhood, but that protection largely disappeared in only a few years, according to a meta-analysis. Effectiveness of the BCG vaccination against tuberculosis in all age groups was 18%. However, when the results were stratified by age, only in children younger […]
Tuberculosis (TB) Treatment, Test, Vaccine & Symptoms
Things to know about tuberculosis (TB) Tuberculosis (TB) is a multisystemic infectious disease caused by the Mycobacterium tuberculosis bacterium. Tuberculosis (TB) is an infectious disease that’s transmitted from person to person. Consumption: an old and once common term for wasting away of the body, particularly from pulmonary tuberculosis (TB) at certain times in the past […]
Body’s response to different strains of tuberculosis could affect transmission: Study could shed light on disease spread, development of resistance
Two strains of the bacterium causing tuberculosis have only minor genetic differences but attack the lungs in completely different fashion, according to Rutgers researchers. The findings, published in the journal Nature Communications, could help break the cycle of rapid transmission of TB, the second-leading infectious killer in the world after COVID-19, according to the World […]
Tuberculosis Skin Test (PPD Skin Test): Results, Treating & Risks
Tuberculosis skin test facts Purified Protein Derivative (PPD) Procedure for Detecting Tuberculosis by McGraw Hill The tuberculosis skin test is another name for the tuberculin test or PPD test. The PPD test determines if someone has developed an immune response to the bacterium that causes tuberculosis (TB). Blood tests for TB are also available, and […]