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Injectable Ketamine Shows Promise in Treatment-Resistant Depression

Twice-weekly subcutaneous ketamine helped alleviate symptoms of treatment-resistant depression, according to the phase III KADS study. Among those who received at least one flexible treatment dose (0.5-0.9 mg/kg), ketamine was more than 12-times better at inducing remission of depression than the benzodiazepine midazolam (remission rate 19.6% vs 2.0%, OR 12.1, 95% CI 2.1-69.2, P=0.005), reported […]

Ketamine Matches ‘Gold Standard’ in Major Depression Trial

SAN FRANCISCO — When it came to improving treatment-resistant major depression in outpatients without psychotic features, ketamine worked just as well as electroconvulsive therapy (ECT), the ELEKT-D randomized trial found. Following a 3-week treatment period, 55.4% of the patients in the ketamine group and 41.2% of those in the ECT group had a treatment response, […]

Healthy changes in diet, activity improved treatment-resistant high blood pressure

People with treatment-resistant hypertension successfully reduced their blood pressure by adopting the Dietary Approaches to Stop Hypertension (DASH) eating plan, losing weight and improving their aerobic fitness by participating in a structured diet and exercise program at a certified cardiac rehabilitation facility, according to new research published today in the American Heart Association’s flagship journal […]

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