Traumatic Experiences Tied to Lower Estrogen Levels in Menopause
ATLANTA — Traumatic life experiences were linked with lower levels of estrogens in menopause, especially for women who got fewer hours of sleep. The finding “underscores the importance of considering trauma in relation to endogenous estrogens, which have implications for women’s midlife health,” researchers noted. In the MsBrain study, postmenopausal women who experienced a traumatic […]
Three in Four Teens Faced Potentially Traumatic Events During the Pandemic
Roughly three out of four high school students reported at least one potentially traumatic experience during the COVID-19 pandemic, a survey showed. While 73.1% of high school students under 18 said they had experienced at least one adverse childhood experience (ACE), 53.2% reported two or more such “preventable, potentially traumatic events,” ranging from food insecurity, […]
Evidence of CTE Rare in Military Personnel
Evidence of chronic traumatic encephalopathy (CTE) was found in a small percentage of brains of deceased military personnel, researchers reported. Among 225 consecutive brains from a brain bank of deceased service members, investigators found signs of CTE in 4.4% (n=10), said Daniel Perl, MD, of the Uniformed Services University in Bethesda, Maryland, and colleagues. Half […]
Blood plasma protein fibrinogen interacts directly with nerve cells to cause brain inflammation
Neuroinflammatory diseases, including Alzheimer’s disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen. These mesh-like fibrin deposits occur outside blood vessels in the brain, contributing to the death of certain central nervous system cells (neurons) that eventually leads to impaired […]
Novel small molecule potently attenuates neuroinflammation in brain and glial cells
Neuroinflammation can worsen outcomes in stroke, traumatic brain injury or spinal cord injury, as well as accelerate neurodegenerative diseases like ALS, Parkinson’s or Alzheimer’s. This suggests that limiting neuroinflammation may represent a promising new approach to treat neurological diseases and neuropathic pain that are driven by neuroinflammation. In a preclinical study published in the journal […]