Urinary Symptoms Linked to Increased Mortality Risk in Men
Moderate and severe lower urinary tract symptoms (LUTS) may be risk factors for mortality in men, according to a Finnish population-based cohort study. In multivariable-adjusted analyses of moderate and severe symptoms (disregarding bother), voiding and storage LUTS were each associated with increased mortality (HR 1.19, 95% CI 1.00-1.40, and HR 1.35, 95% CI 1.13-1.62, respectively), […]
Recurrent UTIs linked to gut microbiome, chronic inflammation: Antibiotics may increase risk of further UTIs by disrupting microbiome
One of the greatest frustrations regarding urinary tract infections (UTIs) is that they so often recur. UTIs are caused by bacteria in the urinary tract and characterized by frequent and painful urination. A round of antibiotics usually clears up the symptoms, but the relief is often temporary: A quarter of women go on to develop […]
Researchers identify potential approaches to modify the vaginal microbiome: Insights may lead to more effective treatments for bacterial vaginosis and improve women’s health outcomes globally
The female genital tract is naturally colonized by mixed communities of bacteria, known as the vaginal microbiome. When these communities are dominated by species such as Lactobacillus crispatus, they provide important protective functions in genital health. But overgrowth of certain other bacterial species is linked to a condition known as bacterial vaginosis (BV). BV affects […]
Novel immune cell population may trigger inflammation in multiple sclerosis and other brain disorders
A group of immune cells that normally protect against inflammation in the gastrointestinal tract may have the opposite effect in multiple sclerosis (MS) and other brain inflammation-related conditions, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian researchers. The results suggest that countering the activity of these cells could be a new therapeutic […]
How fructose in the diet contributes to obesity
Eating fructose appears to alter cells in the digestive tract in a way that enables it to take in more nutrients, according to a preclinical study from investigators at Weill Cornell Medicine and NewYork-Presbyterian. These changes could help to explain the well-known link between rising fructose consumption around the world and increased rates of obesity […]
Can Education Tackle Poor Antibiotic Prescribing in Nursing Homes?
An educational intervention to cut inappropriate antibiotic use for suspected urinary tract infections (UTIs) and lower respiratory tract infections among nursing home residents with advanced dementia had a limited impact in a cluster randomized trial. The multicomponent TRAIN-AD intervention reduced such prescribing by 33% per person-year compared with usual care (adjusted marginal rate difference −0.27, […]