In the NICU, High-Flow Oxygen Boosts Intubation Success on First Attempt
Incorporating nasal high-flow therapy during endotracheal intubation attempts in the neonatal intensive care unit (NICU) increased the chance of success on the first try, a randomized study found. In the SHINE trial of just over 250 intubation attempts at a pair of Australian NICUs, 50% of those that included high-flow therapy had a successful first […]
Another Link Between Prostate Cancer Hormone Tx and Impaired Cognition
Hormonal therapy for advanced prostate cancer, particularly enzalutamide (Xtandi), had a significant association with cognitive impairment, an analysis of a large drug-safety database showed. Traditional hormonal therapy increased the odds of cognitive impairment by 47% versus men who did not receive the therapy. The odds more than doubled among men who received novel androgen receptor […]
Consolidation Intensification Fails in High-Risk Metastatic Ewing Sarcoma
Adding high-dose treosulfan and melphalan as further consolidation therapy for high-risk metastatic Ewing sarcoma failed to improve survival outcomes, a randomized phase III study showed. In an intention-to-treat population of 109 patients receiving standard induction and consolidation therapy, no significant difference was seen in event-free survival (EFS) between a group that also received high-dose treosulfan-melphalan […]
For Men on ADT, Checking Bone Density May Thwart Fractures
Bone density testing in older prostate cancer patients on androgen deprivation therapy (ADT) was significantly associated with a decreased risk for major osteoporotic fractures, but remains little used, a prospective population-based study found. In the cohort of nearly 55,000 men treated with ADT from 2005 to 2015, those who received dual x-ray absorptiometry (DXA) screening […]
New study reveals why HIV remains in human tissue even after antiretroviral therapy: Discovery could open the door to new treatments that improve our immune system’s ability to eliminate the stubborn virus, lead to strides in MS research.
Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system. Now, […]
Grief and Mourning: 7 Stages, Symptoms, Differences & Coping
Adams, K. Managing grief through journal writing. Center for Journal Therapy. 2006. Barry, L. C., Kasl, S. V., Prigerson, H. G. The role of perceived circumstances of death and preparedness for death. American Journal of Geriatric Psychiatry, 10: 447-457, August 2002. Center for Suicide Prevention. Grief after suicide: notes from the literature on qualitative differences […]
Cellular therapy improves signs and symptoms of Duchenne muscular dystrophy: Clinical trial results promising for people with the debilitating disorder
A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people. The therapy appears to be safe and effective in stopping the deterioration of upper limb and […]
What Is ‘Trauma Dumping’? Here’s How To Know If You’re Doing It.
If you’re on the therapy side of TikTok, you may have seen a viral video posted by therapist Ilene Glance that drew so much backlash, she has since deleted her account, @sidequesttherapy. Glance titled the clip “When a client wants to trauma dump first session” and captioned it “Not happening on my watch ever again.” […]
Mindfulness therapy reduces opioid misuse and chronic pain in primary care, according to new research
Results from a new clinical trial demonstrate that an eight-week mindfulness-based therapy — Mindfulness-Oriented Recovery Enhancement (MORE) — decreased opioid use and misuse while reducing chronic pain symptoms, with effects lasting as long as nine months. This is the first large-scale clinical trial to demonstrate that a psychological intervention can simultaneously reduce opioid misuse and […]
Dietary fiber improves outcomes for melanoma patients on immunotherapy
Melanoma patients receiving therapy that makes it easier for their immune system to kill cancer cells respond to treatment better when their diet is rich in fiber, according to a large, international research collaboration that includes the Oregon State University College of Pharmacy. Published today in Science, the study led by the University of Texas […]