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Accelerated Approval Not the Finish Line, Says FDA Commissioner

Drugmakers will no longer be able to slow-walk their accelerated approvals to full regulatory approval, said FDA Commissioner Robert Califf, MD, during the J.P. Morgan Healthcare Conference on Tuesday, while also fielding questions on gene therapies and the modernization of clinical trials, among other topics. Accelerated Approval When asked about the kind of data needed […]

Stroke Data Hint at High Practice Variability Between EMS Agencies

Individual EMS agencies have varied substantially in their stroke case documentation, raising the question of whether problems might also extend to their operations and implementation of stroke protocols, according to preliminary work from Michigan. Based on 147 EMS agencies working in the state, their compliance with documenting time since last known well (LKW) for stroke […]

Proposed Budget Deal Would Partially Delay Cut to Medicare Physician Payments

WASHINGTON — Physician groups wasted no time Tuesday expressing their dismay over a proposed $1.7 trillion budget deal in Congress that would rescind upcoming Medicare physician payment cuts — but only partially. “MGMA is deeply dismayed by the failure of Congress to adequately address the full 4.5% cut to the Medicare conversion factor set to […]

House Subcommittee Report Details Pandemic Failures, Lessons Learned

The House Select Subcommittee on the Coronavirus Crisis discussed their final report highlighting the lessons learned from the COVID-19 pandemic, ranging from the need to invest in next-generation vaccines to the importance of tackling misinformation, during a hearing Wednesday. The report, the culmination of 42 hearings and member briefings, 37 analyses, and testimony from dozens […]

Subcutaneous fat emerges as a protector of females’ brains

Females’ propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopause, scientists report. Males of essentially any age have a greater propensity to deposit fat around the […]

Scientists uncover possible neural link between early life trauma and binge-eating disorder: Discovery may lead to therapeutic targets to treat binge eating, obesity

Nearly 3 percent of Americans suffer from binge-eating disorder at some point their lifetimes, and of them, more than eight in 10 survived childhood abuse, neglect, or other trauma. Now, a Virginia Tech scientist has identified how early life trauma may change the brain to increase the risk of binge eating later in life. Research […]

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